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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 88(1)

A case of reconstruction for triple-negative metaplastic breast cancer that enlarged rapidly during neoadjuvant immunochemotherapy

https://doi.org/10.18999/nagjms.88.1.157
https://doi.org/10.18999/nagjms.88.1.157
5e700469-f048-4f69-9fd9-1c163a78e93e
名前 / ファイル ライセンス アクション
14_Toriyama.pdf 14_Toriyama.pdf (76.2 MB)
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アイテムタイプ itemtype_ver1(1)
公開日 2026-02-27
タイトル
タイトル A case of reconstruction for triple-negative metaplastic breast cancer that enlarged rapidly during neoadjuvant immunochemotherapy
言語 en
著者 Toriyama, Kazuhiro

× Toriyama, Kazuhiro

en Toriyama, Kazuhiro

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Yoshimura, Souji

× Yoshimura, Souji

en Yoshimura, Souji

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Nakamura, Ryota

× Nakamura, Ryota

en Nakamura, Ryota

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Wanifuchi-Endo, Yumi

× Wanifuchi-Endo, Yumi

en Wanifuchi-Endo, Yumi

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Toyama, Tatsuya

× Toyama, Tatsuya

en Toyama, Tatsuya

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
言語 en
キーワード
主題Scheme Other
主題 adjuvant chemotherapy
キーワード
主題Scheme Other
主題 internal mammary artery perforator flap
キーワード
主題Scheme Other
主題 neoadjuvant immunochemotherapy
キーワード
主題Scheme Other
主題 semi-emergency surgery
キーワード
主題Scheme Other
主題 triple-negative metaplastic breast cancer
内容記述
内容記述タイプ Abstract
内容記述 We report a case of reconstruction for triple-negative metaplastic breast cancer that rapidly enlarged during neoadjuvant immunochemotherapy, requiring semi-emergency surgery. A 47-year-old female with metaplastic carcinoma (cT2N0M0, stage IIA) received pembrolizumab, paclitaxel, and carboplatin in a neoadjuvant fashion. Rapid tumor enlargement and axillary lymph node swelling occurred during the first cycle of immunochemotherapy, necessitating semi-emergency surgery to prevent tumor rupture (cT4bN1M0, stage IIIB). Right mastectomy with partial pectoralis major muscle resection and axillary lymph node dissection were performed, exposing the ribs and sternum. Reconstruction utilized an internal mammary artery perforator flap with caudal rotation-advancement, followed by meshed skin grafting. Despite partial epidermal necrosis, wound closure was achieved after 3 weeks. Chemotherapy resumed 4 weeks after surgery; radiation therapy was initiated 4.5 months later. The patient remains disease-free 18 months after surgery. To our knowledge, mastectomy with pectoralis major resection and internal mammary artery perforator flap reconstruction for a triple-negative metaplastic breast cancer that had rapidly progressed during neoadjuvant therapy has not been previously reported.
言語 en
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.88.1.157
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/874.html
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0027-7622
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 88, 号 1, p. 157-161, 発行日 2026-02
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