| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2026-02-27 |
| タイトル |
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|
タイトル |
A case of reconstruction for triple-negative metaplastic breast cancer that enlarged rapidly during neoadjuvant immunochemotherapy |
|
言語 |
en |
| 著者 |
Toriyama, Kazuhiro
Yoshimura, Souji
Nakamura, Ryota
Wanifuchi-Endo, Yumi
Toyama, Tatsuya
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| アクセス権 |
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|
アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利 |
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|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |
|
言語 |
en |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
adjuvant chemotherapy |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
internal mammary artery perforator flap |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
neoadjuvant immunochemotherapy |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
semi-emergency surgery |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
triple-negative metaplastic breast cancer |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
We report a case of reconstruction for triple-negative metaplastic breast cancer that rapidly enlarged during neoadjuvant immunochemotherapy, requiring semi-emergency surgery. A 47-year-old female with metaplastic carcinoma (cT2N0M0, stage IIA) received pembrolizumab, paclitaxel, and carboplatin in a neoadjuvant fashion. Rapid tumor enlargement and axillary lymph node swelling occurred during the first cycle of immunochemotherapy, necessitating semi-emergency surgery to prevent tumor rupture (cT4bN1M0, stage IIIB). Right mastectomy with partial pectoralis major muscle resection and axillary lymph node dissection were performed, exposing the ribs and sternum. Reconstruction utilized an internal mammary artery perforator flap with caudal rotation-advancement, followed by meshed skin grafting. Despite partial epidermal necrosis, wound closure was achieved after 3 weeks. Chemotherapy resumed 4 weeks after surgery; radiation therapy was initiated 4.5 months later. The patient remains disease-free 18 months after surgery. To our knowledge, mastectomy with pectoralis major resection and internal mammary artery perforator flap reconstruction for a triple-negative metaplastic breast cancer that had rapidly progressed during neoadjuvant therapy has not been previously reported. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
Nagoya University Graduate School of Medicine, School of Medicine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
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|
ID登録 |
10.18999/nagjms.88.1.157 |
|
ID登録タイプ |
JaLC |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
URI |
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|
関連識別子 |
https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/874.html |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0027-7622 |
| 収録物識別子 |
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|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2186-3326 |
| 書誌情報 |
en : Nagoya Journal of Medical Science
巻 88,
号 1,
p. 157-161,
発行日 2026-02
|