| アイテムタイプ |
itemtype_ver1(1) |
| 公開日 |
2026-03-05 |
| タイトル |
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タイトル |
Invisible saccule in 3T MRI: insights into inner ear vulnerability and fluid dynamics |
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言語 |
en |
| 著者 |
Yokoyama, Yuya
Kobayashi, Masumi
Yoshida, Tadao
Naganawa, Shinji
Nakashima, Tsutomu
Sone, Michihiko
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| アクセス権 |
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アクセス権 |
embargoed access |
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アクセス権URI |
http://purl.org/coar/access_right/c_f1cf |
| 権利 |
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|
権利情報 |
This is an Accepted Manuscript of an article published by Taylor & Francis Group in ACTA OTO-LARYNGOLOGICA on 20/08/2025, available at: https://doi.org/10.1080/00016489.2025.2546390 |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: The trabecular mesh of the inner ear plays a critical role in maintaining the structure of the vestibular organs, particularly within the pars superior. Cases have been reported in which the saccule cannot be visualized in the pars inferior lacking this structure. Objectives: To investigate the clinical features and endolymphatic hydrops (EH) and perilymphatic enhancement (PE) on MRI in ears with an invisible saccule (IS) and to clarify the mechanism of IS. Materials and methods: Retrospective study of 89 IS ears and 71 contralateral visible saccule (VS) ears from 406 patients with hearing impairment and vertigo between 2021 and 2024. Middle ear disease, schwannoma, perilymphatic fistula, and ears after intratympanic injection were excluded. Results: Compared with VS ears, IS ears had worse hearing, especially in the low-frequency range, and higher PE. Cases diagnosed with Meniere’s disease accounted for 13% of IS, all of which showed EH limited to the cochlea, and PE showed higher in IS ears with vertigo than in those without. Conclusions and significance: The development of IS is associated with loss of anatomical support and subsequent collapse and fistula of the membranous labyrinth, which may cause the breakdown of the blood–labyrinth barrier and changes in lymphatic flow. |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Published online: 20 Aug 2025 |
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言語 |
en |
| 出版者 |
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出版者 |
Taylor & Francis |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプresource |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1080/00016489.2025.2546390 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0001-6489 |
| 書誌情報 |
en : ACTA OTO-LARYNGOLOGICA
巻 145,
号 9,
p. 837-844,
発行日 2025-08-20
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| ファイル公開日 |
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日付 |
2026-08-20 |
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日付タイプ |
Available |