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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Invisible saccule in 3T MRI: insights into inner ear vulnerability and fluid dynamics

http://hdl.handle.net/2237/0002014056
http://hdl.handle.net/2237/0002014056
0393d0c8-33bf-4d18-9785-e0a94c99bea0
名前 / ファイル ライセンス アクション
SOTO-2025-0280.R1_Proof_hi.pdf SOTO-2025-0280.R1_Proof_hi.pdf (829 KB)
 Download is available from 2026/8/20.
アイテムタイプ itemtype_ver1(1)
公開日 2026-03-05
タイトル
タイトル Invisible saccule in 3T MRI: insights into inner ear vulnerability and fluid dynamics
言語 en
著者 Yokoyama, Yuya

× Yokoyama, Yuya

en Yokoyama, Yuya

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Kobayashi, Masumi

× Kobayashi, Masumi

en Kobayashi, Masumi

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Yoshida, Tadao

× Yoshida, Tadao

en Yoshida, Tadao

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Naganawa, Shinji

× Naganawa, Shinji

en Naganawa, Shinji

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Nakashima, Tsutomu

× Nakashima, Tsutomu

en Nakashima, Tsutomu

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Sone, Michihiko

× Sone, Michihiko

en Sone, Michihiko

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アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
権利
権利情報 This is an Accepted Manuscript of an article published by Taylor & Francis Group in ACTA OTO-LARYNGOLOGICA on 20/08/2025, available at: https://doi.org/10.1080/00016489.2025.2546390
言語 en
内容記述
内容記述タイプ Abstract
内容記述 Background: The trabecular mesh of the inner ear plays a critical role in maintaining the structure of the vestibular organs, particularly within the pars superior. Cases have been reported in which the saccule cannot be visualized in the pars inferior lacking this structure. Objectives: To investigate the clinical features and endolymphatic hydrops (EH) and perilymphatic enhancement (PE) on MRI in ears with an invisible saccule (IS) and to clarify the mechanism of IS. Materials and methods: Retrospective study of 89 IS ears and 71 contralateral visible saccule (VS) ears from 406 patients with hearing impairment and vertigo between 2021 and 2024. Middle ear disease, schwannoma, perilymphatic fistula, and ears after intratympanic injection were excluded. Results: Compared with VS ears, IS ears had worse hearing, especially in the low-frequency range, and higher PE. Cases diagnosed with Meniere’s disease accounted for 13% of IS, all of which showed EH limited to the cochlea, and PE showed higher in IS ears with vertigo than in those without. Conclusions and significance: The development of IS is associated with loss of anatomical support and subsequent collapse and fistula of the membranous labyrinth, which may cause the breakdown of the blood–labyrinth barrier and changes in lymphatic flow.
言語 en
内容記述
内容記述タイプ Other
内容記述 Published online: 20 Aug 2025
言語 en
出版者
出版者 Taylor & Francis
言語 en
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1080/00016489.2025.2546390
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0001-6489
書誌情報 en : ACTA OTO-LARYNGOLOGICA

巻 145, 号 9, p. 837-844, 発行日 2025-08-20
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日付 2026-08-20
日付タイプ Available
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