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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 78(2)

Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats

https://doi.org/10.18999/nagjms.78.2.215
https://doi.org/10.18999/nagjms.78.2.215
d2beb7ce-a426-4011-a5f9-c1656111a280
名前 / ファイル ライセンス アクション
19_Hishida.pdf 19_Hishida.pdf (1.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-05-23
タイトル
タイトル Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats
著者 Hishida, Sumiyo

× Hishida, Sumiyo

WEKO 65683

Hishida, Sumiyo

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Ozaki, Noriyuki

× Ozaki, Noriyuki

WEKO 65684

Ozaki, Noriyuki

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Honda, Takashi

× Honda, Takashi

WEKO 65685

Honda, Takashi

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Shigetomi, Toshio

× Shigetomi, Toshio

WEKO 65686

Shigetomi, Toshio

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Ueda, Minoru

× Ueda, Minoru

WEKO 65687

Ueda, Minoru

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Hibi, Hideharu

× Hibi, Hideharu

WEKO 65688

Hibi, Hideharu

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Sugiura, Yasuo

× Sugiura, Yasuo

WEKO 65689

Sugiura, Yasuo

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キーワード
主題Scheme Other
主題 duct ligation
キーワード
主題Scheme Other
主題 atrophy
キーワード
主題Scheme Other
主題 nerve fiber
キーワード
主題Scheme Other
主題 submandibular gland
キーワード
主題Scheme Other
主題 substance P receptor
抄録
内容記述 To clarify the mechanisms underlying the submandibular gland atrophies associated with ptyalolithiasis, morphological changes were examined in the rat submandibular gland following either surgical intervention of the duct or functional blockade at substance P receptors (SPRs). Progressive acinar atrophy was observed after duct ligation or avulsion of periductal tissues. This suggested that damage to periductal tissue involving nerve fibers might contribute to ligation-associated acinar atrophy. Immunohistochemically labeled-substance P positive nerve fibers (SPFs) coursed in parallel with the main duct and were distributed around the interlobular, striated, granular and intercalated duct, and glandular acini. Strong SPR immunoreactivity was observed in the duct. Injection into the submandibular gland of a SPR antagonist induced marked acinar atrophy. The results revealed that disturbance of SPFs and SPRs might be involved in the atrophy of the submandibular gland associated with ptyalolithiasis.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.78.2.215
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 78, 号 2, p. 215-227, 発行日 2016-05
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/782.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/24199
識別子タイプ HDL
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