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Liquid-like behavior of chromatin
http://hdl.handle.net/2237/24585
http://hdl.handle.net/2237/245855af0d6a8-9892-4e0f-a360-7a7af5e4f947
名前 / ファイル | ライセンス | アクション |
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CurrOpnGenDev2016Maeshima.pdf (5.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2016-08-05 | |||||
タイトル | ||||||
タイトル | Liquid-like behavior of chromatin | |||||
言語 | en | |||||
著者 |
Maeshima, Kazuhiro
× Maeshima, Kazuhiro× Ide, Satoru× Hibino, Kayo× Sasai, Masaki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | (c) 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
抄録 | ||||||
内容記述 | Eukaryotic chromatin is a negatively charged long polymer composed of genomic DNA, histones, and various proteins. The charged property causes the chromatin structure to be dynamically changed. These dynamic changes are critical for genome functions such as gene expression because they directly govern the degree of DNA accessibility. Although the chromatin structure is not yet fully understood, currently increasing evidence suggests that chromatin has a dynamic liquid-like structure based on the 10-nm fiber but not the 30-nm fiber. This liquid-like property can drive the process of ‘scanning and targeting genomic DNA,’ which contributes to various genome functions including gene expression and DNA replication, repair, and recombination. Here, we discuss the liquid-like behavior of chromatin and its physical and biological relevance. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | This review comes from a themed issue on Genome architecture and expression, edited by Fred Berger and Pamela Geyer | |||||
言語 | en | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.gde.2015.11.006 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0959-437X | |||||
書誌情報 |
en : Current Opinion in Genetics & Development 巻 37, p. 36-45, 発行日 2016-01 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1016/j.gde.2015.11.006 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/24585 | |||||
識別子タイプ | HDL |