{"created":"2021-03-01T06:30:29.902759+00:00","id":22711,"links":{},"metadata":{"_buckets":{"deposit":"22307f35-4d37-49e4-920c-340c3b174c40"},"_deposit":{"created_by":17,"id":"22711","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"22711"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00022711","sets":["499:508:509:1887"]},"author_link":["93828"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1965-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"66","bibliographicPageStart":"50","bibliographicVolumeNumber":"28","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fatty acid peroxides have been found in the atherosclerotic human aorta by Glavind. A correlation exists between the extent of the atherosclerotic changes and the content of lipid peroxides. It may be inferred that the presence of peroxides in the aorta brings about a disturbance in the function of the arterial wall and gives rise to atherosclerotic changes. Vitamin E, which prevents the peroxidation of lipids, might suppress the atherogenesis. X-ray irradiation, which induces the auto-oxidation of lipids, might promote the process of the atherogenesis. From these considerations, the present investigation was performed. The determinations of peroxides were carried out on the rabbit aorta by the ammonium thiocyanate method. A correlation existed between the extent of the atherosclerotic changes and the content of lipid peroxides. The aortas with no atherosclerotic changes contained only small amount of peroxides. Peroxides of the rabbit aorta were determined by the method of TBA. Vitamin E injection prevented the lipid peroxidation in the aortas and livers. Furthermore, Vitamin E suppressed the atherosclerotic changes. Peroxides were produced by X-ray irradiation in the aortic wall and liver of the rabbit. Whole body X-ray irradiation promoted the progress of atherosclerotic changes in cholesterol fed rabbit, and produced atheroma-like plaque in the thoracic aorta of the rabbit. The respiration of the aorta of rat was decreased by peroxides added in the diet. However, the respiration of liver was not influenced. The activity of cytochrome oxidase was more inhibited than that of succinic dehydrogenase. In vitro effect of peroxides on the respiration of the aorta of rats was also observed.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.28.1.50","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/281/281.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"IWAKAMI, MINORU","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93828","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-22"}],"displaytype":"detail","filename":"v28n1p50_66.pdf","filesize":[{"value":"2.6 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"label":"v28n1p50_66.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/22711/files/v28n1p50_66.pdf"},"version_id":"29c65224-53bb-44fe-b9ff-b54f95ad0579"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Peroxides as a Factor of Atherosclerosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Peroxides as a Factor of Atherosclerosis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1887"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-09-26"},"publish_date":"2016-09-26","publish_status":"0","recid":"22711","relation_version_is_last":true,"title":["Peroxides as a Factor of Atherosclerosis"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T04:45:14.151489+00:00"}