{"created":"2021-03-01T06:30:31.485690+00:00","id":22735,"links":{},"metadata":{"_buckets":{"deposit":"9af13b8f-a3e2-4a4e-b696-c8da8cc3ed1d"},"_deposit":{"created_by":17,"id":"22735","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"22735"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00022735","sets":["499:508:509:1888"]},"author_link":["93884"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1966-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"154","bibliographicPageStart":"139","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Adrenal venous 17-hydroxycorticosteroid (17-OHCS) output in response to insulin, histamine and synthetic lysine vasopressin (L-8-V) intravenous administration was determined in nembutal-anesthetized and adrenal-vein cannulated dogs. Dexamethasone pretreatment prevented the adrenal cortical activation provoked by insulin. But when the doses of insulin were increased adrenal cortical response appeared, whereas the larger doses of dexamethasone pretreatment suppressed the adrenal cortical response caused by the increased doses of insulin administration. The quantitative correlationship between the intensity of stress which was represented by the amount of insulin administered and the amount of corticosteroids needed for blocking the stress-induced adrenal cortical activation was observed. Such correlation was also observed between histamine-induced adrenal cortical activation and dexamethasone pretreatment. In hypophysectomized dogs, neither insulin nor histamine could cause adrenal cortical response. On the other hand, dexamethasone pretraetment did not prevent the adrenal cortical activation caused by L-8-V administration, but only the shortening of responding time was observed. L-8-V infused in hypophysectomized dogs did not cause appreciable adrenal cortical activation except for some minimal rise in 17-OHCS output. The enormous doses of dexamethasone did seemingly suppress the adrenal cortical activation caused by less doses of L-8-V. This suggests that massive doses of glucocorticoids might affect pituitary itself.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.29.2.139","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/292/292.html","subitem_relation_type_select":"URI"}}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ASANO, HARUYOSHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93884","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-22"}],"displaytype":"detail","filename":"v29n2p139_154.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"label":"v29n2p139_154.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/22735/files/v29n2p139_154.pdf"},"version_id":"59faf0ce-1769-4055-bce4-bfa34fd03d12"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Insulin, Histamine and Vasopressin on Pituitary-adrenocortical Secretion with or without Dexamethasone Pretreatment","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Insulin, Histamine and Vasopressin on Pituitary-adrenocortical Secretion with or without Dexamethasone Pretreatment","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1888"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-09-27"},"publish_date":"2016-09-27","publish_status":"0","recid":"22735","relation_version_is_last":true,"title":["Effects of Insulin, Histamine and Vasopressin on Pituitary-adrenocortical Secretion with or without Dexamethasone Pretreatment"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T04:45:58.922272+00:00"}