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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Application of histogram analysis for the evaluation of vascular permeability in glioma by the K2 parameter obtained with the dynamic susceptibility contrast method: Comparisons with Ktrans obtained with the dynamic contrast enhance method and cerebral blood volume

http://hdl.handle.net/2237/25085
http://hdl.handle.net/2237/25085
ccb68005-00ca-4bf5-a18b-243ef842bb08
名前 / ファイル ライセンス アクション
MRI-D-16-00009R1r_Redacted.pdf MRI-D-16-00009R1r_Redacted.pdf ファイル公開:2017/09/01 (378.3 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2016-11-22
タイトル
タイトル Application of histogram analysis for the evaluation of vascular permeability in glioma by the K2 parameter obtained with the dynamic susceptibility contrast method: Comparisons with Ktrans obtained with the dynamic contrast enhance method and cerebral blood volume
言語 en
著者 Taoka, Toshiaki

× Taoka, Toshiaki

WEKO 67410

en Taoka, Toshiaki

Search repository
Kawai, Hisashi

× Kawai, Hisashi

WEKO 67411

en Kawai, Hisashi

Search repository
Nakane, Toshiki

× Nakane, Toshiki

WEKO 67412

en Nakane, Toshiki

Search repository
Hori, Saeka

× Hori, Saeka

WEKO 67413

en Hori, Saeka

Search repository
Ochi, Tomoko

× Ochi, Tomoko

WEKO 67414

en Ochi, Tomoko

Search repository
Miyasaka, Toshiteru

× Miyasaka, Toshiteru

WEKO 67415

en Miyasaka, Toshiteru

Search repository
Sakamoto, Masahiko

× Sakamoto, Masahiko

WEKO 67416

en Sakamoto, Masahiko

Search repository
Kichikawa, Kimihiko

× Kichikawa, Kimihiko

WEKO 67417

en Kichikawa, Kimihiko

Search repository
Naganawa, Shinji

× Naganawa, Shinji

WEKO 67418

en Naganawa, Shinji

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
キーワード
主題Scheme Other
主題 Permeability imaging
キーワード
主題Scheme Other
主題 K2
キーワード
主題Scheme Other
主題 Perfusion imaging
キーワード
主題Scheme Other
主題 MRI
キーワード
主題Scheme Other
主題 Glioma
抄録
内容記述 Purpose: The “K2” value is a factor that represents the vascular permeability of tumors and can be calculated from datasets obtained with the dynamic susceptibility contrast (DSC) method. The purpose of the current study was to correlate K2 with Ktrans, which is a well-established permeability parameter obtained with the dynamic contrast enhance (DCE) method, and determine the usefulness of K2 for glioma grading with histogram analysis. Methods: The subjects were 22 glioma patients (Grade II: 5, III: 6, IV: 11) who underwent DSC studies, including eight patients in which both DSC and DCE studies were performed on separate days within 10 days. We performed histogram analysis of regions of interest of the tumors and acquired 20th percentile values for leakage-corrected cerebral blood volume (rCBV20%ile), K2 (K220%ile), and for patients who underwent a DCE study, Ktrans (Ktrans20%ile). We evaluated the correlation between K220%ile and Ktrans20%ile and the statistical difference between rCBV20%ile and K220%ile. Results: We found a statistically significant correlation between K220%ile and Ktrans20%ile (r = 0.717, p < 0.05). rCBV20%ile showed a significant difference between Grades II and III and between Grades II and IV, whereas K220%ile showed a statistically significant (p < 0.05) difference between Grades II and IV and between Grades III and IV. Conclusions: The K2 value calculated from the DSC dataset, which can be obtained with a short acquisition time, showed a correlation with Ktrans obtained with the DCE method and may be useful for glioma grading when analyzed with histogram analysis.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.mri.2016.04.020
ISSN
収録物識別子タイプ PISSN
収録物識別子 0730-725X
書誌情報 en : Magnetic Resonance Imaging

巻 34, 号 7, p. 896-901, 発行日 2016-09
著者版フラグ
値 author
URI
識別子 http://dx.doi.org/10.1016/j.mri.2016.04.020
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/25085
識別子タイプ HDL
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