{"created":"2021-03-01T06:30:47.223258+00:00","id":22974,"links":{},"metadata":{"_buckets":{"deposit":"1e181d40-8c36-4929-975d-683de5aa010a"},"_deposit":{"id":"22974","owners":[],"pid":{"revision_id":0,"type":"depid","value":"22974"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00022974","sets":["1903:1904:1905"]},"author_link":["67840","67841","67842","67843","67844"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"348","bibliographicPageStart":"343","bibliographicVolumeNumber":"478","bibliographic_titles":[{"bibliographic_title":"Biochemical and Biophysical Research Communications","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Transglutaminase (TGase) catalyzes protein cross-linking reactions essential for several biological processes. In differentiating keratinocytes, TG1 (keratinocyte-type) is crucial for the cross-linking of substrate proteins required for the complete formation of the cornified envelop, a proteinaceous supermolecule located in the outermost layer of the epidermis. TG1 expressions and its substrate were induced in cultured keratinocytes at differentiation-stage specific manner. In the cultured keratinocytes, we used the TG1-specific substrate peptide, which enables the specific detection of enzymatic activity to investigate its induction patterns. As a further application of the substrate peptide, several substrate candidates of TG1 that may be essential for cornified envelope formation were identified and characterized.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"http://dx.doi.org/10.1016/j.bbrc.2016.07.051"},{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/25155"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.bbrc.2016.07.051","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0006-291X","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamane, Miki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"67840","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugimura, Kayoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"67841","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawasaki, Hiroko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"67842","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tatsukawa, Hideki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"67843","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hitomi, Kiyotaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"67844","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-01"}],"displaytype":"detail","filename":"BBRC-S-16-06867_Redacted.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BBRC-S-16-06867_Redacted.pdf ファイル公開：2017/09/01","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/22974/files/BBRC-S-16-06867_Redacted.pdf"},"version_id":"6f4793b7-9038-4127-a2e9-fc6c00779e36"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Transglutaminase","subitem_subject_scheme":"Other"},{"subitem_subject":"Keratinocyte","subitem_subject_scheme":"Other"},{"subitem_subject":"Epidermis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["1905"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-12-07"},"publish_date":"2016-12-07","publish_status":"0","recid":"22974","relation_version_is_last":true,"title":["Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:12:15.807793+00:00"}