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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Prevalence and Distribution of Ossified Lesions in the Whole Spine of Patients with Cervical Ossification of the Posterior Longitudinal Ligament A Multicenter Study (JOSL CT study)

http://hdl.handle.net/2237/25419
http://hdl.handle.net/2237/25419
a5347204-f484-4eb8-a40b-7f4c0506b39c
名前 / ファイル ライセンス アクション
journal_pone_0160117.pdf journal_pone_0160117.pdf (2.4 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-01-18
タイトル
タイトル Prevalence and Distribution of Ossified Lesions in the Whole Spine of Patients with Cervical Ossification of the Posterior Longitudinal Ligament A Multicenter Study (JOSL CT study)
言語 en
著者 Hirai, Takashi

× Hirai, Takashi

WEKO 68860

en Hirai, Takashi

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Yoshii, Toshitaka

× Yoshii, Toshitaka

WEKO 68861

en Yoshii, Toshitaka

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Iwanami, Akio

× Iwanami, Akio

WEKO 68862

en Iwanami, Akio

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Takeuchi, Kazuhiro

× Takeuchi, Kazuhiro

WEKO 68863

en Takeuchi, Kazuhiro

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Mori, Kanji

× Mori, Kanji

WEKO 68864

en Mori, Kanji

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Yamada, Tsuyoshi

× Yamada, Tsuyoshi

WEKO 68865

en Yamada, Tsuyoshi

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Wada, Kanichiro

× Wada, Kanichiro

WEKO 68866

en Wada, Kanichiro

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Koda, Masao

× Koda, Masao

WEKO 68867

en Koda, Masao

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Matsuyama, Yukihiro

× Matsuyama, Yukihiro

WEKO 68868

en Matsuyama, Yukihiro

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Takeshita, Katsushi

× Takeshita, Katsushi

WEKO 68869

en Takeshita, Katsushi

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Abematsu, Masahiko

× Abematsu, Masahiko

WEKO 68870

en Abematsu, Masahiko

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Haro, Hirotaka

× Haro, Hirotaka

WEKO 68871

en Haro, Hirotaka

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Watanabe, Masahiko

× Watanabe, Masahiko

WEKO 68872

en Watanabe, Masahiko

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Watanabe, Kei

× Watanabe, Kei

WEKO 68873

en Watanabe, Kei

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Ozawa, Hiroshi

× Ozawa, Hiroshi

WEKO 68874

en Ozawa, Hiroshi

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Kanno, Haruo

× Kanno, Haruo

WEKO 68875

en Kanno, Haruo

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Imagama, Shiro

× Imagama, Shiro

WEKO 68876

en Imagama, Shiro

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Fujibayashi, Shunsuke

× Fujibayashi, Shunsuke

WEKO 68877

en Fujibayashi, Shunsuke

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Yamazaki, Masashi

× Yamazaki, Masashi

WEKO 68878

en Yamazaki, Masashi

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Matsumoto, Morio

× Matsumoto, Morio

WEKO 68879

en Matsumoto, Morio

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Nakamura, Masaya

× Nakamura, Masaya

WEKO 68880

en Nakamura, Masaya

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Okawa, Atsushi

× Okawa, Atsushi

WEKO 68881

en Okawa, Atsushi

Search repository
Kawaguchi, Yoshiharu

× Kawaguchi, Yoshiharu

WEKO 68882

en Kawaguchi, Yoshiharu

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2016 Hirai et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
抄録
内容記述 Ossification of the posterior longitudinal ligament (OPLL) can cause severe and irreversible paralysis in not only the cervical spine but also the thoracolumbar spine. To date, however, the prevalence and distribution of OPLL in the whole spine has not been precisely evaluated in patients with cervical OPLL. Therefore, we conducted a multi-center study to comprehensively evaluate the prevalence and distribution of OPLL using multi-detector computed tomography (CT) images in the whole spine and to analyze what factors predict the presence of ossified lesions in the thoracolumbar spine in patients who were diagnosed with cervical OPLL by plain X-ray. Three hundred and twenty-two patients with a diagnosis of cervical OPLL underwent CT imaging of the whole spine. The sum of the levels in which OPLL was present in the whole spine was defined as the OP-index and used to evaluate the extent of ossification. The distribution of OPLL in the whole spine was compared between male and female subjects. In addition, a multiple regression model was used to ascertain related factors that affected the OP-index. Among patients with cervical OPLL, women tended to have more ossified lesions in the thoracolumbar spine than did men. A multiple regression model revealed that the OP-index was significantly correlated with the cervical OP-index, sex (female), and body mass index. Furthermore, the prevalence of thoracolumbar OPLL in patients with a cervical OP-index ≥ 10 was 7.8 times greater than that in patients with a cervical OP-index ≤ 5. The results of this study reveal that the extent of OPLL in the whole spine is significantly associated with the extent of cervical OPLL, female sex, and obesity.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 PLOS
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1371/journal.pone.0160117
ISSN
収録物識別子タイプ EISSN
収録物識別子 1932-6203
書誌情報 en : PLOS ONE

巻 11, 号 8, p. e0160117-e0160117, 発行日 2016-08-22
著者版フラグ
値 publisher
URI
識別子 http://dx.doi.org/10.1371/journal.pone.0160117
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/25419
識別子タイプ HDL
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