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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 79(1)

High-dose intravenous pulse steroid therapy for optic disc swelling and subretinal fluid in non-arteritic anterior ischemic optic neuropathy

https://doi.org/10.18999/nagjms.79.1.103
https://doi.org/10.18999/nagjms.79.1.103
527ca57d-0463-4c5b-9643-f0365872d26a
名前 / ファイル ライセンス アクション
36_Takayama.pdf 36_Takayama.pdf (13.0 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-02-23
タイトル
タイトル High-dose intravenous pulse steroid therapy for optic disc swelling and subretinal fluid in non-arteritic anterior ischemic optic neuropathy
著者 Takayama, Kei

× Takayama, Kei

WEKO 69544

Takayama, Kei

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Kaneko, Hiroki

× Kaneko, Hiroki

WEKO 69545

Kaneko, Hiroki

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Kachi, Shu

× Kachi, Shu

WEKO 69546

Kachi, Shu

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Ra, Eimei

× Ra, Eimei

WEKO 69547

Ra, Eimei

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Ito, Yasuki

× Ito, Yasuki

WEKO 69548

Ito, Yasuki

Search repository
Terasaki, Hiroko

× Terasaki, Hiroko

WEKO 69549

Terasaki, Hiroko

Search repository
キーワード
主題Scheme Other
主題 ION
キーワード
主題Scheme Other
主題 macular edema
キーワード
主題Scheme Other
主題 NAION
キーワード
主題Scheme Other
主題 OCT
キーワード
主題Scheme Other
主題 systemic steroids
抄録
内容記述 Non-arteritic anterior ischemic optic neuropathy (NAION) is a disease with microvascular abnormality that causes acute optic disc swelling (ODS) and, in severe cases, subretinal fluid (SRF) accumulation. ODS causes compartment syndrome and subsequent axonal degeneration and loss of retinal ganglion cells by apoptosis. No treatment modalities have been effective, although some cases improved after the intake of oral systemic steroids. We reported a case of a 72-year-old man who was referred due to a visual defect in the right eye. At first presentation, visual acuity and visual field were disturbed; critical flicker frequency (CFF) was decreased; and optic coherence tomography (OCT) showed ODS and SRF. Microscopic examination revealed parapapillary hemorrhage and fluorescence angiography showed non-filling, temporal-superior choroidal lesion adjacent to the optic disc at an early phase. After high-dose intravenous steroid treatment, SRF and ODS were decreased, and completely resolved after 30 days. Visual acuity and CFF were improved, and visual field was enlarged. High-dose intravenous steroids could possibly resolve SRF and ODS and improve visual function of patients with NAION. Some cases in NAION improved visual acuity and visual function in natural course, more cases were needed to evaluate the efficiency.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.79.1.103
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 79, 号 1, p. 103-108, 発行日 2017-02
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/791.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/25628
識別子タイプ HDL
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