{"created":"2021-03-01T06:32:37.397104+00:00","id":24656,"links":{},"metadata":{"_buckets":{"deposit":"52902a88-0017-42e5-afe1-c819de929bf9"},"_deposit":{"id":"24656","owners":[],"pid":{"revision_id":0,"type":"depid","value":"24656"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00024656","sets":["320:321:322"]},"author_link":["73058","73059","73060","73061","73062","73063","73064","73065"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1495","bibliographicPageStart":"1487","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"Annals of Biomedical Engineering","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A novel apparatus for the multifaceted evaluation of artery function was developed. It measures endothelial and smooth muscle functions and the pressure–strain elastic modulus (Ep). A rigid airtight chamber with an ultrasound probe was attached to the upper arm to manipulate the transmural pressure of the brachial artery. Endothelial function was measured via a standard flow-mediated dilation (FMD) protocol. Smooth muscle function was evaluated via a myogenic contraction of the artery following the application of negative pressure to the chamber and was named pressure-mediated contraction (PMC). Ep was obtained by measuring the instantaneous increase in the artery diameter following the negative pressure application. The PMC and FMD values had a significant negative correlation with age, indicating that the age-related decrease in FMD is caused by the decay of endothelial and smooth muscle function. A consideration of PMC may help improve the accuracy of artery function measurement. Ep in subjects aged >40 years was found to be significantly higher in the supra-physiological pressure range than in the physiological one (p = 0.02); this did not occur in younger subjects. Artery stiffening may begin in the supra-physiological range, and this stiffness may also be used for the diagnosis of atherosclerosis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"https://doi.org/10.1007/s10439-017-1810-z"},{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/26875"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10439-017-1810-z","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"The final publication is available at Springer via https://doi.org/10.1007/s10439-017-1810-z","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0090-6964","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yaguchi, Toshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73058","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Cong, Yalin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73059","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimo, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73060","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kurokawa, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73061","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugita, Shukei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73062","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagayama, Kazuaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73063","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masuda, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73064","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Takeo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73065","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-01"}],"displaytype":"detail","filename":"Paper49forRepository.pdf","filesize":[{"value":"8.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Paper49forRepository.pdf ファイル公開：2018/06/01","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/24656/files/Paper49forRepository.pdf"},"version_id":"9c5b6dbb-fc89-491f-8c83-1ad27491fffa"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["322"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-08-03"},"publish_date":"2017-08-03","publish_status":"0","recid":"24656","relation_version_is_last":true,"title":["A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:14:03.489575+00:00"}