{"created":"2021-03-01T06:32:45.340445+00:00","id":24776,"links":{},"metadata":{"_buckets":{"deposit":"04247852-149c-4589-9b0a-0e40b8e41a7a"},"_deposit":{"id":"24776","owners":[],"pid":{"revision_id":0,"type":"depid","value":"24776"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00024776","sets":["1903:1904:1905"]},"author_link":["73655","73656","73657","73658","73659","73660"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"97","bibliographicPageStart":"84","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"Molecular Microbiology","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Nutritional restrictions such as calorie restrictions are known to increase the lifespan of various organisms. Here, we found that a restriction of sulfur extended the chronological lifespan (CLS) of the fission yeast Schizosaccharomyces pombe. The restriction decreased cellular size, RNA content, and ribosomal proteins and increased sporulation rate. These responses depended on Ecl1 family genes, the overexpression of which results in the extension of CLS. We also showed that the Zip1 transcription factor results in the sulfur restriction-dependent expression of the ecl1^+ gene. We demonstrated that a decrease in ribosomal activity results in the extension of CLS. Based on these observations, we propose that sulfur restriction extends CLS through Ecl1 family genes in a ribosomal activity-dependent manner.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"http://doi.org/10.1111/mmi.13686"},{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/26998"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/mmi.13686","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is the peer reviewed version of the following article: [H.Ohtsuka, M.Takinami, T.Shimasaki,T.Hibi,H.Murakami,and H.Aiba,Molecular Microbiology.v.105,n.1, 2017,p.84-97]which has been published in final form at [http://doi.org/10.1111/mmi.13686]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0950-382X","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohtsuka, Hokuto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73655","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takinami, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73656","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimasaki, Takafumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73657","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hibi, Takahide","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73658","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Murakami, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73659","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aiba, Hirofumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"73660","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-01"}],"displaytype":"detail","filename":"Total.pdf","filesize":[{"value":"8.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Total.pdf ファイル公開:2018/07/01","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/24776/files/Total.pdf"},"version_id":"443ebf61-fb41-41a4-89a0-f61ec8a77c23"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["1905"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"24776","relation_version_is_last":true,"title":["Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:15:14.186574+00:00"}