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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Successful Blood Transfusion Management of a Living Donor Liver Transplant Recipient in the Presence of Anti-Jrª: A Case Report

http://hdl.handle.net/2237/27160
http://hdl.handle.net/2237/27160
f63fed9c-2bd8-4b3c-86aa-e4ccb2c86208
名前 / ファイル ライセンス アクション
Kurata_JRa_paper-1.pdf Kurata_JRa_paper-1.pdf ファイル公開日:2018/09/01 (342.3 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-12-11
タイトル
タイトル Successful Blood Transfusion Management of a Living Donor Liver Transplant Recipient in the Presence of Anti-Jrª: A Case Report
言語 en
著者 Kurata, Nobuhiko

× Kurata, Nobuhiko

WEKO 74335

en Kurata, Nobuhiko

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Onishi, Yasuharu

× Onishi, Yasuharu

WEKO 74336

en Onishi, Yasuharu

Search repository
Kamei, Hideya

× Kamei, Hideya

WEKO 74337

en Kamei, Hideya

Search repository
Hori, Tomohide

× Hori, Tomohide

WEKO 74338

en Hori, Tomohide

Search repository
Komagome, Masahiko

× Komagome, Masahiko

WEKO 74339

en Komagome, Masahiko

Search repository
Kato, Chiaki

× Kato, Chiaki

WEKO 74340

en Kato, Chiaki

Search repository
Matsushita, Tadashi

× Matsushita, Tadashi

WEKO 74341

en Matsushita, Tadashi

Search repository
Ogura, Yasuhiro

× Ogura, Yasuhiro

WEKO 74342

en Ogura, Yasuhiro

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
キーワード
主題Scheme Other
主題 anti-Jrª
キーワード
主題Scheme Other
主題 blood transfusion
キーワード
主題Scheme Other
主題 liver transplantation
抄録
内容記述 A 48-year-old Japanese woman was diagnosed with Budd-Chiari syndrome and transferred for possible living donor liver transplantation (LDLT). Examinations before LDLT revealed that the recipient had anti-Jrª and preformed donor-specific antiehuman leukocyte antigen (HLA) antibodies (DSA). Rituximab was administrated at 16 days prior to the patient’s scheduled LDLT for the prophylaxis of antibody-mediated rejection by DSA. The clinical significance of anti-Jrª has not been clearly established because of the rarity of this antibody, so we discussed blood transfusion strategy with the Department of Blood Transfusion Service and prepared for Jrª -negative packed red blood cells (RBCs). Intraoperative blood salvage was used during LDLT procedures to reduce the use of packed RBCs. Although post-transplantation graft function was excellent, a total of 44 U of Jrª -negative RBCs were transfused during the entire perioperative period. Because suffi- cient amounts of Jrª -negative packed RBCs were supplied, Jrª mismatched blood transfusion was avoided. The patient was discharged from our hospital on postoperative day 102 without clinical evidence of any blood transfusionerelated adverse events. Although there are some controversies of blood transfusion related to anti- Jrª antibodies, the current strategies of blood transfusion for liver transplantation with anti-Jrª are as follows: (1) sufficient supply and transfusion of Jrª -negative matched packed RBCs and (2) application of intraoperative blood salvage to reduce the total amount of rare blood type RBCs. These strategies may be changed when the mechanism of anti-Jrª alloimmunization is fully understood in the future.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.transproceed.2017.06.009
ISSN
収録物識別子タイプ PISSN
収録物識別子 0041-1345
書誌情報 en : Transplantation Proceedings

巻 49, 号 7, p. 1604-1607, 発行日 2017-09
著者版フラグ
値 author
URI
識別子 http://doi.org/10.1016/j.transproceed.2017.06.009
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/27160
識別子タイプ HDL
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