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Successful Blood Transfusion Management of a Living Donor Liver Transplant Recipient in the Presence of Anti-Jrª: A Case Report
http://hdl.handle.net/2237/27160
http://hdl.handle.net/2237/27160f63fed9c-2bd8-4b3c-86aa-e4ccb2c86208
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-12-11 | |||||
タイトル | ||||||
タイトル | Successful Blood Transfusion Management of a Living Donor Liver Transplant Recipient in the Presence of Anti-Jrª: A Case Report | |||||
言語 | en | |||||
著者 |
Kurata, Nobuhiko
× Kurata, Nobuhiko× Onishi, Yasuharu× Kamei, Hideya× Hori, Tomohide× Komagome, Masahiko× Kato, Chiaki× Matsushita, Tadashi× Ogura, Yasuhiro |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | anti-Jrª | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | blood transfusion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver transplantation | |||||
抄録 | ||||||
内容記述 | A 48-year-old Japanese woman was diagnosed with Budd-Chiari syndrome and transferred for possible living donor liver transplantation (LDLT). Examinations before LDLT revealed that the recipient had anti-Jrª and preformed donor-specific antiehuman leukocyte antigen (HLA) antibodies (DSA). Rituximab was administrated at 16 days prior to the patient’s scheduled LDLT for the prophylaxis of antibody-mediated rejection by DSA. The clinical significance of anti-Jrª has not been clearly established because of the rarity of this antibody, so we discussed blood transfusion strategy with the Department of Blood Transfusion Service and prepared for Jrª -negative packed red blood cells (RBCs). Intraoperative blood salvage was used during LDLT procedures to reduce the use of packed RBCs. Although post-transplantation graft function was excellent, a total of 44 U of Jrª -negative RBCs were transfused during the entire perioperative period. Because suffi- cient amounts of Jrª -negative packed RBCs were supplied, Jrª mismatched blood transfusion was avoided. The patient was discharged from our hospital on postoperative day 102 without clinical evidence of any blood transfusionerelated adverse events. Although there are some controversies of blood transfusion related to anti- Jrª antibodies, the current strategies of blood transfusion for liver transplantation with anti-Jrª are as follows: (1) sufficient supply and transfusion of Jrª -negative matched packed RBCs and (2) application of intraoperative blood salvage to reduce the total amount of rare blood type RBCs. These strategies may be changed when the mechanism of anti-Jrª alloimmunization is fully understood in the future. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.transproceed.2017.06.009 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0041-1345 | |||||
書誌情報 |
en : Transplantation Proceedings 巻 49, 号 7, p. 1604-1607, 発行日 2017-09 |
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著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | http://doi.org/10.1016/j.transproceed.2017.06.009 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/27160 | |||||
識別子タイプ | HDL |