{"created":"2021-03-01T06:32:56.681248+00:00","id":24947,"links":{},"metadata":{"_buckets":{"deposit":"ede536c9-a71a-4c21-bcfd-5439225220f6"},"_deposit":{"id":"24947","owners":[],"pid":{"revision_id":0,"type":"depid","value":"24947"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00024947","sets":["1179:2033:2034"]},"author_link":["74365","74366","74367","74368","74369","74370","74371","74372","74373","74374"],"control_number":"24947","item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"1585","bibliographicPageStart":"1558","bibliographicVolumeNumber":"525","bibliographic_titles":[{"bibliographic_title":"Journal of Comparative Neurology","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The structure of the neural circuitry of the cerebellum, which functions in some types of motor learning and coordination, is generally conserved among vertebrates. However, some cerebellar features are species-specific. It is not clear which genes are involved in forming these conserved and species-specific structures and functions. Here, using zebrafish transgenic larvae expressing fluorescent proteins in granule cells, Purkinje cells, or other cerebellar neurons and glial cells, we isolated each type of cerebellar cells by fluorescence-activated cell sorting and profiled their gene expressions by RNA sequencing and in situ hybridization. We identified genes that were upregulated in granule cells or Purkinje cells, including many genes that are also expressed in mammalian cerebella. A comparison of the transcriptomes in granule cells and Purkinje cells in zebrafish larvae revealed that more developmental genes are expressed in granule cells, whereas more neuronal-function genes are expressed in Purkinje cells. We further found that some genes that are upregulated in granule cells or Purkinje cells are also expressed in the cerebellum-like structures. Our data provide a platform for understanding the development and function of the cerebellar neural circuits in zebrafish, and the evolution of cerebellar circuits in vertebrates.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"http://doi.org/10.1002/cne.24114"},{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/27169"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1002/cne.24114","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is the peer reviewed version of the following article: [Journal of Comparative Neurology. v.525, n.7, 2017, p.1558-1585], which has been published in final form at [http://doi.org/10.1002/cne.24114/]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0021-9967","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takeuchi, Miki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74365","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaguchi, Shingo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74366","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakakibara, Masayoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74367","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hayashi, Takuto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74368","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsuda, Koji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74369","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hara, Yuichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74370","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanegashima, Chiharu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74371","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimizu, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74372","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuraku, Shigehiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74373","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hibi, Masahiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"74374","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-06-27"}],"displaytype":"detail","filename":"Supplementary Table3.xls","filesize":[{"value":"304 KB"}],"format":"application/vnd.ms-excel","licensetype":"license_note","mimetype":"application/vnd.ms-excel","url":{"label":"Supplementary Table3.xls 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Table1.xls ファイル公開日:2018/05/01","objectType":"dataset","url":"https://nagoya.repo.nii.ac.jp/record/24947/files/Supplementary Table1.xls"},"version_id":"6b3eebaf-3964-40ec-96eb-d4cbc3bfcfc9"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-01"}],"displaytype":"detail","filename":"Takeuchi_J_Comp_Neurol_2017.pdf","filesize":[{"value":"2.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Takeuchi_J_Comp_Neurol_2017.pdf ファイル公開日:2018/05/01","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/24947/files/Takeuchi_J_Comp_Neurol_2017.pdf"},"version_id":"17072139-d7f8-4d5a-b1c2-4d418a93c221"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"RNA-seq","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebellar gene enrichment","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebellum-like structures","subitem_subject_scheme":"Other"},{"subitem_subject":"RRID:ZIRC_ZL1","subitem_subject_scheme":"Other"},{"subitem_subject":"RRID: AB_10013361","subitem_subject_scheme":"Other"},{"subitem_subject":"RRID: SCR_001370","subitem_subject_scheme":"Other"},{"subitem_subject":"RRID: SCR_001120","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Gene Expression Profiling of Granule Cells and Purkinje Cells in the Zebrafish Cerebellum","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Gene Expression Profiling of Granule Cells and Purkinje Cells in the Zebrafish Cerebellum","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["2034"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-12-12"},"publish_date":"2017-12-12","publish_status":"0","recid":"24947","relation_version_is_last":true,"title":["Gene Expression Profiling of Granule Cells and Purkinje Cells in the Zebrafish Cerebellum"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:31:08.140465+00:00"}