{"_buckets": {"deposit": "4282dfb4-734e-4227-b01c-c48afa318080"}, "_deposit": {"id": "24951", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24951"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00024951"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "1877", "bibliographicPageStart": "1870", "bibliographicVolumeNumber": "26", "bibliographic_titles": [{"bibliographic_title": "PROTEIN SCIENCE"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "WBSCR16 (Williams-Beuren Syndrome Chromosomal Region 16) gene is located in alarge deletion region of Williams-Beuren syndrome (WBS), which is a neurodevelopmental disorder.Although the relationship between WBSCR16 and WBS remains unclear, it has been reported thatWBSCR16 is a member of a functional module that regulates mitochondrial 16S rRNA abundanceand intra-mitochondrial translation. WBSCR16 has RCC1 (Regulator of Chromosome Condensation1)-like amino acid sequence repeats but the function of WBSCR16 appears to be different fromthat of other RCC1 superfamily members. Here, we demonstrate that WBSCR16 localizes to mito-chondria in HeLa cells, and report the crystal structure of WBSCR16 deter mined to 2.0 A\u02daresolutionusing multi-wavelength anomalous diffraction. WBSCR16 adopts the seven-bladed b-propeller foldcharacteristic of RCC1-like proteins. A comparison of the WBSCR16 structure with that of RCC1and other RCC1-like proteins reveals that, although many of the residues buried in the core of theb-propeller are highly conserved, the surface residues are poorly conserved and conformationally divergent.", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1002/pro.3210"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/27173"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Wiley"}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\"This is the peer reviewed version of the following article: [Koyama, M., Sasaki, T., Sasaki, N. and Matsuura, Y. (2017), Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria. Protein Science, 26: 1870\u20131877], which has been published in final form at [http://doi.org/10.1002/pro.3210]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.\""}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0961-8368", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Koyama, Masako"}], "nameIdentifiers": [{"nameIdentifier": "74383", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sasaki, Taeko"}], "nameIdentifiers": [{"nameIdentifier": "74384", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sasaki, Narie"}], "nameIdentifiers": [{"nameIdentifier": "74385", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsuura, Yoshiyuki"}], "nameIdentifiers": [{"nameIdentifier": "74386", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-09-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "koyama2017ProtSci_for_depository3.pdf", "filesize": [{"value": "881.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 881200.0, "url": {"label": "koyama2017ProtSci_for_depository3.pdf \u30d5\u30a1\u30a4\u30eb\u516c\u958b\u65e5:2018/09/01", "url": "https://nagoya.repo.nii.ac.jp/record/24951/files/koyama2017ProtSci_for_depository3.pdf"}, "version_id": "f48bbf24-1503-4939-b265-542420955a6e"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "WBSCR16", "subitem_subject_scheme": "Other"}, {"subitem_subject": "RCC1-like protein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Williams-Beuren syndrome", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mitochondrial translation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mitoribosome", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria"}]}, "item_type_id": "10", "owner": "1", "path": ["336/695/696"], "permalink_uri": "http://hdl.handle.net/2237/27173", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2017-12-19"}, "publish_date": "2017-12-19", "publish_status": "0", "recid": "24951", "relation": {}, "relation_version_is_last": true, "title": ["Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria"], "weko_shared_id": null}