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  1. B100 理学部/理学研究科
  2. B100a 雑誌掲載論文
  3. 学術雑誌

A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death

http://hdl.handle.net/2237/00027945
http://hdl.handle.net/2237/00027945
d5fa1f36-2c54-47ce-a9fc-f93c093e0bcf
名前 / ファイル ライセンス アクション
Lin20180122.pdf Lin20180122 (2.6 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-05-08
タイトル
タイトル A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death
言語 en
著者 Lin, Hsing-An

× Lin, Hsing-An

WEKO 76310

en Lin, Hsing-An

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Sato, Yoshikatsu

× Sato, Yoshikatsu

WEKO 76311

en Sato, Yoshikatsu

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Segawa, Yasutomo

× Segawa, Yasutomo

WEKO 76312

en Segawa, Yasutomo

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Nishihara, Taishi

× Nishihara, Taishi

WEKO 76313

en Nishihara, Taishi

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Sugimoto, Nagisa

× Sugimoto, Nagisa

WEKO 76314

en Sugimoto, Nagisa

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Scott, Lawrence T.

× Scott, Lawrence T.

WEKO 76315

en Scott, Lawrence T.

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Higashiyama, Tetsuya

× Higashiyama, Tetsuya

WEKO 76316

en Higashiyama, Tetsuya

Search repository
Itami, Kenichiro

× Itami, Kenichiro

WEKO 76317

en Itami, Kenichiro

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is the peer reviewed version of the following article: [H.-A. Lin, Y. Sato, Y. Segawa, T. Nishihara, N. Sugimoto, L. T. Scott, T. Higashiyama, K. Itami, Angew. Chem. Int. Ed. 2018, 57, 2874.], which has been published in final form at [https://doi.org/10.1002/anie.201713387]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
キーワード
主題Scheme Other
主題 arenes
キーワード
主題Scheme Other
主題 cell death
キーワード
主題Scheme Other
主題 chromophores
キーワード
主題Scheme Other
主題 fluorescence
キーワード
主題Scheme Other
主題 polycycles
キーワード
主題Scheme Other
主題 warped nanographenes
抄録
内容記述 Nanographene, a small piece of graphene, has attracted unprecedented interest across diverse scientific disciplines particularly in organic electronics. The biological applications of nanographenes, such as bioimaging, cancer therapies and drug delivery, provide significant opportunities for breakthroughs in the field. However, the intrinsic aggregation behavior and low solubility of nanographenes, which stem from their flat structures, hamper their development for bioapplications. Herein, we report a water‐soluble warped nanographene (WNG) that can be easily synthesized by sequential regioselective C−H borylation and cross‐coupling reactions of the saddle‐shaped WNG core structure. The saddle‐shaped structure and hydrophilic tetraethylene glycol chains impart high water solubility to the WNG. The water‐soluble WNG possesses a range of promising properties including good photostability and low cytotoxicity. Moreover, the water‐soluble WNG was successfully internalized into HeLa cells and promoted photoinduced cell death.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2019-03-05
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Wiley
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/anie.201713387
ISSN
収録物識別子タイプ PISSN
収録物識別子 14337851
書誌情報 en : Angewandte Chemie International Edition

巻 57, 号 11, p. 2874-2878, 発行日 2018-03-05
著者版フラグ
値 author
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