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A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death
http://hdl.handle.net/2237/00027945
http://hdl.handle.net/2237/00027945d5fa1f36-2c54-47ce-a9fc-f93c093e0bcf
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-05-08 | |||||
タイトル | ||||||
タイトル | A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death | |||||
言語 | en | |||||
著者 |
Lin, Hsing-An
× Lin, Hsing-An× Sato, Yoshikatsu× Segawa, Yasutomo× Nishihara, Taishi× Sugimoto, Nagisa× Scott, Lawrence T.× Higashiyama, Tetsuya× Itami, Kenichiro |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | This is the peer reviewed version of the following article: [H.-A. Lin, Y. Sato, Y. Segawa, T. Nishihara, N. Sugimoto, L. T. Scott, T. Higashiyama, K. Itami, Angew. Chem. Int. Ed. 2018, 57, 2874.], which has been published in final form at [https://doi.org/10.1002/anie.201713387]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | arenes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cell death | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chromophores | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fluorescence | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polycycles | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | warped nanographenes | |||||
抄録 | ||||||
内容記述 | Nanographene, a small piece of graphene, has attracted unprecedented interest across diverse scientific disciplines particularly in organic electronics. The biological applications of nanographenes, such as bioimaging, cancer therapies and drug delivery, provide significant opportunities for breakthroughs in the field. However, the intrinsic aggregation behavior and low solubility of nanographenes, which stem from their flat structures, hamper their development for bioapplications. Herein, we report a water‐soluble warped nanographene (WNG) that can be easily synthesized by sequential regioselective C−H borylation and cross‐coupling reactions of the saddle‐shaped WNG core structure. The saddle‐shaped structure and hydrophilic tetraethylene glycol chains impart high water solubility to the WNG. The water‐soluble WNG possesses a range of promising properties including good photostability and low cytotoxicity. Moreover, the water‐soluble WNG was successfully internalized into HeLa cells and promoted photoinduced cell death. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | ファイル公開:2019-03-05 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Wiley | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1002/anie.201713387 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 14337851 | |||||
書誌情報 |
en : Angewandte Chemie International Edition 巻 57, 号 11, p. 2874-2878, 発行日 2018-03-05 |
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著者版フラグ | ||||||
値 | author |