{"created":"2021-03-01T06:34:15.019546+00:00","id":26333,"links":{},"metadata":{"_buckets":{"deposit":"375aa022-80b1-4b19-b718-edb3d3f0d19b"},"_deposit":{"created_by":17,"id":"26333","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"26333"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00026333","sets":["499:508:509:2109"]},"author_link":["85095","85096","85097","85098","85099","85100","85101"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"429","bibliographicPageStart":"423","bibliographicVolumeNumber":"80","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Hepatic carcinosarcoma (HCS) generally presents in advanced stages, demonstrates aggressive behavior, and has a poor prognosis. Other than curative primary resection, no effective treatment options exist. We present a case of resected HCS with four repeat resections for solitary lymph node recurrence followed by chemoradiotherapy with doxorubicin and ifosfamide. A 67-year-old Japanese man was admitted to our hospital for evaluation of an asymptomatic hepatic tumor. The patient underwent right hepatectomy with a presumptive preoperative diagnosis of atypical hepatocellular carcinoma. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as HCS containing osteosarcoma and chondrosarcoma components. After the initial surgery, the patient underwent four additional resections for solitary lymph node HCS recurrence, and then underwent chemoradiotherapy with doxorubicin and ifosfamide for an unresectable lymph node recurrence. Chemotherapy was stopped after two cycles because of severe adverse events, although chemoradiotherapy markedly reduced the size of the lymph node recurrence and provided a progression-free survival of 12 months. Thirty-seven months after the initial surgery, the patient died of cardiac invasion of multiple mediastinal lymph node metastases. The clinical course outlined in this case report suggests that chemoradiotherapy with doxorubicin and ifosfamide for metastatic HCS may prolong survival in patients with unresectable lesions.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.80.3.423","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/803.html ","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kurita, Daisuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85095","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mokuno, Yasuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85096","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsubara, Hideo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85097","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kaneko, Hirokazu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85098","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shamoto, Mikihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85099","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satou, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85100","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iyomasa, Shinsuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"85101","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-09-05"}],"displaytype":"detail","filename":"15_Kurita.pdf","filesize":[{"value":"3.3 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"label":"15_Kurita.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/26333/files/15_Kurita.pdf"},"version_id":"d85a0ead-d360-477f-be3c-d4a69b4e1d28"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hepatic carcinosarcoma","subitem_subject_scheme":"Other"},{"subitem_subject":"chemoradiotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"doxorubicin","subitem_subject_scheme":"Other"},{"subitem_subject":"ifosfamide","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Primary hepatic carcinosarcoma with multimodal treatment","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Primary hepatic carcinosarcoma with multimodal treatment","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["2109"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-09-05"},"publish_date":"2018-09-05","publish_status":"0","recid":"26333","relation_version_is_last":true,"title":["Primary hepatic carcinosarcoma with multimodal treatment"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T04:20:05.196366+00:00"}