@article{oai:nagoya.repo.nii.ac.jp:00027165, author = {Okamoto, Haruka and Toh, Kohei and Mochizuki, Takuya and Nakatsuji, Hidefumi and Sakakura, Akira and Hatano, Manabu and Ishihara, Kazuaki}, issue = {23}, journal = {Synthesis}, month = {Dec}, note = {Chiral BINOL-derived pyrophosphoric acid catalysts were developed and used for the regio- and enantioselective aza-Friedel–Crafts reaction of phenols with aldimines. ortho/para-Directing phenols could react at the para-position selectively with moderate to good enantioselectivities. Moreover, the gram-scale transformation of a product into the key intermediate for the antifungal agent (R)-bifonazole was demonstrated., ファイル公開:2019/12/01}, pages = {4577--4590}, title = {Chiral Pyrophosphoric Acid Catalysts for the para-Selective and Enantioselective Aza-Friedel–Crafts Reaction of Phenols}, volume = {50}, year = {2018} }