{"_buckets": {"deposit": "1711f99f-1645-4af1-9c7c-04721123edb3"}, "_deposit": {"id": "27942", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "27942"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00027942", "sets": ["322"]}, "author_link": ["90970", "90971"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-01-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "774", "bibliographicPageStart": "762", "bibliographicVolumeNumber": "15", "bibliographic_titles": [{"bibliographic_title": "Journal of Chemical Theory and Computation", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Heterogeneity is essential for multicomponent lipid membranes. Especially, sterol-induced domain formation in membranes has recently attracted attention because of its biological importance. To investigate such membrane domains at the molecular level, coarse-grained molecular dynamics (CG-MD) simulations are a promising approach since they allow one to consider the temporal and spatial scales involved in domain formation. In this work, we present a new CG force field, named SPICA, which can accurately predict domain formation within various lipids in membranes. The SPICA force field was developed as an extension of a previous CG model, known as SDK (Shinoda–DeVane–Klein), in which membrane properties such as tension, elasticity, and structure are well reproduced. By examining domain formation in a series of ternary lipid bilayers, we observed a separation into liquid-ordered and liquid-disordered phases fully consistent with experimental observations. Importantly, it is shown that the SPICA force field can detect the different phase behavior that results from subtle differences in the lipid composition of the bilayer.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "ファイル公開：2020-01-08", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "ACS Publications", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1021/acs.jctc.8b00987", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "“This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Journal of Chemical Theory and Computation], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/articlesonrequest/AOR-8jyNBbDxuMJjIPBjauyS].”", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN（print）", "attribute_value_mlt": [{"subitem_source_identifier": "1549-9618", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Seo, Sangjae", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "90970", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shinoda, Wataru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "90971", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-01-08"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "submission_version.pdf", "filesize": [{"value": "3.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 3900000.0, "url": {"label": "submission_version", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/27942/files/submission_version.pdf"}, "version_id": "067720c5-c6a0-496e-9ed8-373996340d2a"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "SPICA Force Field for Lipid Membranes: Domain Formation Induced by Cholesterol", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "SPICA Force Field for Lipid Membranes: Domain Formation Induced by Cholesterol", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["322"], "permalink_uri": "http://hdl.handle.net/2237/00030141", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2019-05-09"}, "publish_date": "2019-05-09", "publish_status": "0", "recid": "27942", "relation": {}, "relation_version_is_last": true, "title": ["SPICA Force Field for Lipid Membranes: Domain Formation Induced by Cholesterol"], "weko_shared_id": -1}