{"created":"2021-03-01T06:35:59.209220+00:00","id":27947,"links":{},"metadata":{"_buckets":{"deposit":"c84f5d9e-2687-4c66-ad5e-aee8fa12fcf1"},"_deposit":{"id":"27947","owners":[],"pid":{"revision_id":0,"type":"depid","value":"27947"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00027947","sets":["1917:1918:1919"]},"author_link":["90988","90989","90990"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-01-16","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"830","bibliographicPageStart":"825","bibliographicVolumeNumber":"141","bibliographic_titles":[{"bibliographic_title":"Journal of the American Chemical Society","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report the palladium(II)-catalyzed transfer hydration of cyanohydrins to α-hydroxyamides by using carboxamides as water donors. This method enables selective hydration of various aldehyde- and ketone-derived cyanohydrins to afford α-mono- and α,α-disubstituted-α-hydroxyamides, respectively, under mild conditions (50 °C, 10 min). The direct conversion of fenofibrate, a drug bearing a benzophenone moiety, into a functionalized α,α-diaryl-α-hydroxyamide was achieved by means of a hydrocyanation–transfer hydration sequence. Preliminary kinetic studies and the synthesis of a site-specifically 18O-labeled α-hydroxyamide demonstrated the carbonyl oxygen transfer from the carboxamide reagent into the α-hydroxyamide product.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"ファイル公開：2020-01-16","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"ACS Publications","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1021/jacs.8b12877","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"“This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Journal of the American Chemical Society], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/articlesonrequest/AOR-G2mCKTXg7y5BCEnWAmU9].”","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_61":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0002-7863","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kanda, Tomoya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"90988","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naraoka, Asuka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"90989","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naka, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"90990","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-16"}],"displaytype":"detail","filename":"SubmittedText.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SubmittedText","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/27947/files/SubmittedText.pdf"},"version_id":"fd824978-e6e3-4569-b451-d57555041749"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Catalytic Transfer Hydration of Cyanohydrins to α-Hydroxyamides","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Catalytic Transfer Hydration of Cyanohydrins to α-Hydroxyamides","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["1919"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-05-09"},"publish_date":"2019-05-09","publish_status":"0","recid":"27947","relation_version_is_last":true,"title":["Catalytic Transfer Hydration of Cyanohydrins to α-Hydroxyamides"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:50:37.902263+00:00"}