@article{oai:nagoya.repo.nii.ac.jp:00028231, author = {Inada, Haruki and Shibuya, Masatoshi and Yamamoto, Yoshihiko}, issue = {3}, journal = {Organic Letters}, month = {Feb}, note = {A practical telescoping three-step process for the syntheses of α-amino acids from the corresponding 1,2-diols has been developed. This process enables the direct synthesis of free α-amino acids without any protection/deprotection step. This method was also effective for the preparation of a 15N-labeled α-amino acid. 1,2-Diols bearing α,β-unsaturated ester moieties afforded bicyclic α-amino acids through intramolecular [3 + 2] cycloadditions. A preliminary study suggests that the resultant α-amino acids are resolvable by aminoacylases with almost complete selectivity., ファイル公開:2020-02-01}, pages = {709--713}, title = {Direct Synthesis of Free α-Amino Acids by Telescoping Three-Step Process from 1,2-Diols}, volume = {21}, year = {2019} }