{"created":"2021-03-01T06:36:18.111315+00:00","id":28234,"links":{},"metadata":{"_buckets":{"deposit":"c63d749c-d8b6-440a-8270-8a79340cc2ce"},"_deposit":{"id":"28234","owners":[],"pid":{"revision_id":0,"type":"depid","value":"28234"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00028234","sets":["499:500:501"]},"author_link":["91965","91966","91967","91968","91969","91970","91971","91972","91973"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-03-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"405","bibliographicPageStart":"400","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"International Journal of Urology","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: To investigate the long‐term efficacy and safety of periurethral injection of autologous adipose‐derived regenerative cells for the treatment of post‐prostatectomy stress urinary incontinence. Methods: A total of 13 patients with persistent stress urinary incontinence after prostate surgery (radical prostatectomy, 10 patients; holmium laser enucleation of the prostate, three patients) underwent periurethral injection of adipose‐derived regenerative cells and were followed up for >4 years. A 24‐h pad test was carried out for four consecutive days in each evaluation period, and changes in the mean daily leakage volume during the 4 days from baseline to 60 months after treatment were evaluated. Results: The mean follow‐up period was 69 months (range 55–72 months). The mean leakage volume/24 h in all patients changed from 260.7 g to 152.7 g. Urinary incontinence progressively improved up to 12 months after treatment in 10 patients, who maintained improvement up to the final assessment, with the mean daily leakage volume decreasing from 281.5 g to 119.0 g (reduction rate 57.7%). The other three patients showed no improvement at 1 year and at the final assessment. After the perioperative period, significant adverse events or prostate‐specific antigen increase were not observed during long‐term follow up. Conclusions: The present findings suggest that periurethral injection of autologous adipose‐derived regenerative cells is a safe and feasible treatment modality with long‐term efficacy for patients with male stress urinary incontinence caused by urethral sphincter deficiency.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"ファイル公開：2020-03-03","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/iju.13886","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is the peer reviewed version of the following article: [Gotoh, M. , Yamamoto, T. , Shimizu, S. , Matsukawa, Y. , Kato, M. , Majima, T. , Takai, S. , Funahashi, Y. and Toriyama, K. (2019), Treatment of male stress urinary incontinence using autologous adipose‐derived regenerative cells: Long‐term efficacy and safety. Int. J. Urol., 26: 400-405. doi:10.1111/iju.13886], which has been published in final form at [https://doi.org/10.1111/iju.13886]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_61":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0919-8172","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Gotoh, Momokazu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91965","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Tokunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91966","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimizu, Shinobu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91967","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsukawa, Yoshihisa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91968","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Masashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91969","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Majima, Tsuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91970","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takai, Shun","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91971","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Funahashi, Yasuhito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91972","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Toriyama, Kazuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"91973","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-03"}],"displaytype":"detail","filename":"ADRCs.pdf","filesize":[{"value":"308.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ADRCs","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/28234/files/ADRCs.pdf"},"version_id":"31b66691-de89-4b11-8993-7e996443c1f3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"adipose‐derived regenerative cells","subitem_subject_scheme":"Other"},{"subitem_subject":"cell therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"male","subitem_subject_scheme":"Other"},{"subitem_subject":"prostatectomy","subitem_subject_scheme":"Other"},{"subitem_subject":"stress urinary incontinence","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Treatment of male stress urinary incontinence using autologous adipose-derived regenerative cells: Long-term efficacy and safety","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Treatment of male stress urinary incontinence using autologous adipose-derived regenerative cells: Long-term efficacy and safety","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["501"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-06-13"},"publish_date":"2019-06-13","publish_status":"0","recid":"28234","relation_version_is_last":true,"title":["Treatment of male stress urinary incontinence using autologous adipose-derived regenerative cells: Long-term efficacy and safety"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:20:40.231748+00:00"}