{"created":"2021-03-01T06:36:44.058625+00:00","id":28628,"links":{},"metadata":{"_buckets":{"deposit":"7b0d53b6-8e5c-4ec5-bc1a-9fb51b07f962"},"_deposit":{"id":"28628","owners":[],"pid":{"revision_id":0,"type":"depid","value":"28628"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00028628","sets":["499:500:501"]},"author_link":["93772","93773","93774","93775"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"655","bibliographicPageStart":"651","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Modern Rheumatology","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: Kawasaki disease (KD) is one of the most common childhood vasculitides. Some serological studies have suggested an etiological relationship between KD and human herpesvirus (HHV)-6 or HHV-7. However, primary or reactivated HHV-6 and -7 has not been fully investigated in patients with KD. Methods: Twenty-three patients with KD were prospectively enrolled in this study. Peripheral blood was collected in the acute and convalescence phases, and HHV-6 and -7 viral loads were measured by real-time PCR. Results: In the acute phase, HHV-6 and -7 DNA was detected in 7 (30%) patients each, compared to 13 (57%) and 9 (39%) patients in the convalescence phase, respectively. HHV-6 and -7 DNA loads were significantly higher in the convalescence phase than in the acute phase. Significant increases in HHV-6 and -7 DNA loads were not observed in disease control patients. Taking into account HHV-6 and -7 serostatus, reactivation of HHV-6 and -7 was observed in 7 and 9 patients, respectively. KD patients with HHV-6 reactivation showed higher C-reactive protein levels and more frequently required steroid therapies than patients without reactivation. Conclusion: HHV-6 and -7 reactivation is frequent in KD patients. HHV-6 reactivation might exacerbate the severity of KD.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Published online: 05 Sep 2018","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Taylor & Francis","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1080/14397595.2018.1510758","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is an Accepted Manuscript of an article published by Taylor & Francis Group in Modern Rheumatology on 05/09/2018, available online: http://www.tandfonline.com/10.1080/14397595.2018.1510758. ","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_61":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"1439-7595","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kawano, Yoshihiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93772","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawada, Jun-ichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93773","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagai, Noriko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93774","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Yoshinori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93775","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-18"}],"displaytype":"detail","filename":"MR_Kawano_repository.pdf","filesize":[{"value":"314.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"MR_Kawano_repository","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/28628/files/MR_Kawano_repository.pdf"},"version_id":"db737c92-52dd-4fc6-95db-3226cc7b26e7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Human herpesvirus 6","subitem_subject_scheme":"Other"},{"subitem_subject":"human herpesvirus 7","subitem_subject_scheme":"Other"},{"subitem_subject":"Kawasaki disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Reactivation of human herpesviruses 6 and 7 in Kawasaki disease","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Reactivation of human herpesviruses 6 and 7 in Kawasaki disease","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["501"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-10-18"},"publish_date":"2019-10-18","publish_status":"0","recid":"28628","relation_version_is_last":true,"title":["Reactivation of human herpesviruses 6 and 7 in Kawasaki disease"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:21:35.189693+00:00"}