{"created":"2021-03-01T06:36:57.635772+00:00","id":28837,"links":{},"metadata":{"_buckets":{"deposit":"3ec03881-bd3c-4ada-9d40-3b895e97b743"},"_deposit":{"id":"28837","owners":[],"pid":{"revision_id":0,"type":"depid","value":"28837"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00028837","sets":["499:500:501"]},"author_link":["94903","94904","94905","94906","94907","94908","94909","94910"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"513","bibliographicPageStart":"507","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"Pituitary","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Functional pituitary adenomas (FPAs) lacking a well-defined pseudocapsule can invade the adjacent pituitary gland. In such situations, peel-off resection of the adjacent pituitary gland after selective adenomectomy might lead to complete tumor removal, resulting in optimal endocrinological outcomes. Here, we present the significance of peel-off resection of the pituitary gland in patients with FPA in whom complete extracapsular tumor removal cannot be achieved. Methods: We performed a retrospective review of 21 patients with FPA who underwent transsphenoidal surgery (TSS). After selective adenomectomy, peel-off resection of the adjacent pituitary gland was performed in 13 patients because complete extracapsular resection could not be achieved, while peel-off resection was not performed in the remaining 8 patients because complete extracapsular resection was accomplished. The clinical outcomes of these groups were compared. The pituitary tissues obtained by peel-off resection were pathologically examined for tumor cells. Results: Early postoperative biochemical remission was achieved in 20 patients (95.2%). Anterior pituitary functions were not aggravated postoperatively in any patient: however, transient diabetes insipidus (DI) occurred in 2 patients. There were no statistically significant differences in the clinical outcomes of the two groups. A pseudocapsule was pathologically detected in the adjacent anterior pituitary even in patients in whom no pseudocapsule was intraoperatively detected. Tumor cells were pathologically detected in 7 (58.3%) of 12 pituitary tissues examined. Conclusions: Peel-off resection of the pituitary gland, which can remove a small tumor cell remnant in the adjacent pituitary, might maximize the effectiveness of TSS with minimal impact on postoperative pituitary function.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"ファイル公開：2020/10/01","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s11102-019-00980-w","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"“This is a post-peer-review, pre-copyedit version of an article published in [Pituitary]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11102-019-00980-w”.","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_61":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"1386-341X","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nagata, Yuichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94903","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takeuchi, Kazuhito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94904","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Taiki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94905","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94906","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawabata, Teppei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94907","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimoyama, Yoshie","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94908","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inoshita, Naoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94909","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wakabayashi, Toshihiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"94910","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-01"}],"displaytype":"detail","filename":"Manuscript.pdf","filesize":[{"value":"194.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Manuscript","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/28837/files/Manuscript.pdf"},"version_id":"aa0ffc9e-1c7e-49f5-989d-646793fdb0ff"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Pituitary resection","subitem_subject_scheme":"Other"},{"subitem_subject":"Transsphenoidal surgery","subitem_subject_scheme":"Other"},{"subitem_subject":"Pseudocapsule","subitem_subject_scheme":"Other"},{"subitem_subject":"Pituitary adenoma","subitem_subject_scheme":"Other"},{"subitem_subject":"Acromegaly","subitem_subject_scheme":"Other"},{"subitem_subject":"Cushing disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["501"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-12-20"},"publish_date":"2019-12-20","publish_status":"0","recid":"28837","relation_version_is_last":true,"title":["Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:21:01.834339+00:00"}