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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 82(1)

A prospective trial to evaluate treatment effects of a β-hydroxy-β-methylbutyrate containing nutrient for leakage at the anastomotic site after esophagectomy

https://doi.org/10.18999/nagjms.82.1.33
https://doi.org/10.18999/nagjms.82.1.33
29b1b628-822d-4c96-a3e0-10f50696e70c
名前 / ファイル ライセンス アクション
05_Kanda.pdf 05_Kanda.pdf (604.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-02-26
タイトル
タイトル A prospective trial to evaluate treatment effects of a β-hydroxy-β-methylbutyrate containing nutrient for leakage at the anastomotic site after esophagectomy
著者 Kanda, Mitsuro

× Kanda, Mitsuro

WEKO 96288

Kanda, Mitsuro

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Koike, Masahiko

× Koike, Masahiko

WEKO 96289

Koike, Masahiko

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Fukaya, Masahide

× Fukaya, Masahide

WEKO 96290

Fukaya, Masahide

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Miyata, Kazushi

× Miyata, Kazushi

WEKO 96291

Miyata, Kazushi

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Tanaka, Chie

× Tanaka, Chie

WEKO 96292

Tanaka, Chie

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Kobayashi, Daisuke

× Kobayashi, Daisuke

WEKO 96293

Kobayashi, Daisuke

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Hayashi, Masamichi

× Hayashi, Masamichi

WEKO 96294

Hayashi, Masamichi

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Yamada, Suguru

× Yamada, Suguru

WEKO 96295

Yamada, Suguru

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Nakayama, Goro

× Nakayama, Goro

WEKO 96296

Nakayama, Goro

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Murotani, Kenta

× Murotani, Kenta

WEKO 96297

Murotani, Kenta

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Fujiwara, Michitaka

× Fujiwara, Michitaka

WEKO 96298

Fujiwara, Michitaka

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Nagino, Masato

× Nagino, Masato

WEKO 96299

Nagino, Masato

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Kodera, Yasuhiro

× Kodera, Yasuhiro

WEKO 96300

Kodera, Yasuhiro

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キーワード
主題Scheme Other
主題 esophagectomy
キーワード
主題Scheme Other
主題 leakage at the anastomotic site
キーワード
主題Scheme Other
主題 b-hydroxy-b-methylbutyrate
抄録
内容記述 Anastomotic leakage after esophagectomy is associated with prolonged hospitalization and increased medical cost. Additionally, it sometimes leads to a fatal condition and impaired postoperative quality of life. During the process of wound healing, β-hydroxy-β-methylbutyrate (HMB) is important for collagen biosynthesis. An open-label prospective intervention trial has been designed to evaluate the treatment effect of an enteral nutrient containing HMB with arginine and glutamine (Abound, Abbott Japan Co., Ltd.) for leakage at the anastomotic site after esophagectomy. Patients in whom leakage at the anastomotic site developed within 14 days after esophagectomy are eligible and Abound (24 g) is administered for 14 days through an enteral feeding tube. The target sample size is 10. The primary endpoint is duration between diagnosis and cure of leakage. Surgical procedure, safety, length of fasting, drainage placement and hospital stay, and nutritional status are determined as secondary endpoints. A historical control consisting of 20 patients who had leakage at the anastomotic site after esophagectomy between 2005 and 2018 at Nagoya University Hospital is compared with enrolled patients.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.82.1.33
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/821.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 82, 号 1, p. 33-37, 発行日 2020-02
著者版フラグ
値 publisher
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