@article{oai:nagoya.repo.nii.ac.jp:00029361, author = {Hiraiwa, Hiroaki and Okumura, Takahiro and Shimizu, Shinya and Arao, Yoshihito and Oishi, Hideo and Kato, Hiroo and Kuwayama, Tasuku and Yamaguchi, Shogo and Haga, Tomoaki and Yokoi, Tsuyoshi and Kondo, Toru and Sugiura, Yuki and Kano, Naoaki and Watanabe, Naoki and Fukaya, Kenji and Furusawa, Kenji and Sawamura, Akinori and Morimoto, Ryota and Fujimoto, Kazuro and Mutsuga, Masato and Usui, Akihiko and Murohara, Toyoaki}, issue = {1}, journal = {Nagoya Journal of Medical Science}, month = {Feb}, note = {We herein report the long-term changes in cardiac function and pathological findings after successful explantation of a left ventricular assist device in a 42-year-old patient with anthracycline-induced cardiomyopathy with reworsening heart failure. Endomyocardial biopsy samples revealed that the cardiomyocyte diameter decreased and collagen volume fraction increased just after left ventricular assist device explantation. The collagen volume fraction decreased after 6 months, despite preserved systolic function. At 5 years after left ventricular assist device explantation, the systolic function markedly decreased and cardiomyocyte diameter increased. Pathological changes of the myocardium may enable the identification of cardiac dysfunction prior to echocardiographic changes in patients with reworsening heart failure after left ventricular assist device explantation.}, pages = {129--134}, title = {Pathological changes of the myocardium in reworsening of anthracycline-induced cardiomyopathy after explant of a left ventricular assist device}, volume = {82}, year = {2020} }