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Different factors are associated with conventional adenoma and serrated colorectal neoplasia
https://doi.org/10.18999/nagjms.82.2.335
https://doi.org/10.18999/nagjms.82.2.3357636f33d-db49-4bc3-be2e-c8986fd4e081
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2020-06-01 | |||||
タイトル | ||||||
タイトル | Different factors are associated with conventional adenoma and serrated colorectal neoplasia | |||||
著者 |
Zorron Cheng Tao Pu, Leonardo
× Zorron Cheng Tao Pu, Leonardo× Rana, Khizar× Singh, Gurfarmaan× Nakamura, Masanao× Yamamura, Takeshi× Koay, Doreen Siew Ching× Ovenden, Amanda× Edwards, Suzanne× Ruszkiewicz, Andrew× Hirooka, Yoshiki× Fujishiro, Mitsuhiro× Burt, Alastair D× Singh, Rajvinder |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | colonoscopy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | comorbidity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | risk factors | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | colonic polyps | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | colonic neoplasms | |||||
抄録 | ||||||
内容記述 | Current data shows there are differences in factors associated with colorectal neoplasia based on geographical location and cultural settings. There are no studies focusing on the association between environmental factors and colorectal polyps in Australia. The aim of this study was to prospectively evaluate the association of various factors with different colorectal neoplasia histology. We utilized a simplified one-page questionnaire for patients undergoing colonoscopy for information on age; gender; comorbidities; family history of colorectal cancer; physical activity; smoking; diet; alcohol intake; and body mass index. Factors were then evaluated for association with the presence of: (1) neoplastic lesions; (2) conventional adenomas; (3) neoplastic serrated polyps; (4) any lesions (past and present); and (5) hyperplastic polyps. 291 procedures and 260 patients were included. Factors with a p-value < 0.2 in a univariate regression were included in an initial multivariable regression model. Backwards elimination was then performed, removing one predictor at a time until only significant predictors remained. In the final multivariable model, age≥65, male gender, type-2 diabetes mellitus, active smoking and family history of colorectal cancer were found to be statistically significant predictors for the presence of colorectal neoplasia. However, the significant predictors found for conventional adenomas (older age, male gender and smoking) were different from the significant predictors for neoplastic serrated polyps (type-2 diabetes mellitus and family history of colorectal cancer). Older age, male gender, type-2 diabetes mellitus, and smoking were significantly associated with the presence of colorectal neoplasia. The factors associated with conventional adenomas differed from those associated with neoplastic serrated polyps. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.82.2.335 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 82, 号 2, p. 335-343, 発行日 2020-05 |
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著者版フラグ | ||||||
値 | publisher |