@article{oai:nagoya.repo.nii.ac.jp:00030140,
 author = {Murakami, Keigo and Toma, Tatsuya and Fukuyama, Tohru and Yokoshima, Satoshi},
 issue = {15},
 journal = {Angewandte Chemie International Edition},
 month = {Apr},
 note = {A total synthesis of tetrodotoxin was accomplished. A Diels–Alder reaction between a known enone and a siloxy diene gave a tricyclic product, the steric bias of which was used to construct the remaining stereogenic centers. A nitrogen atom was introduced either by a four‐step sequence involving a Curtius rearrangement, or a three‐step sequence featuring a newly developed transformation of a terminal alkyne into a nitrile. Introduction of the guanidine moiety followed by the formation of the heterocyclic system by cascade reactions led to tetrodotoxin., ファイル公開：2021-04-06},
 pages = {6253--6257},
 title = {Total Synthesis of Tetrodotoxin},
 volume = {59},
 year = {2020}
}