{"_buckets": {"deposit": "58733bae-4496-412c-8a78-e90cda9f5cf9"}, "_deposit": {"id": "30628", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "30628"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00030628", "sets": ["2533"]}, "author_link": ["101799"], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1997-03-31", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "131", "bibliographicPageStart": "91", "bibliographicVolumeNumber": "48", "bibliographic_titles": [{"bibliographic_title": "Memoirs of the School of Engineering, Nagoya University", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Some chemical modifications of natural nucleosides based on the general organic chemistry have been carried out. Base catalyzed elimination reactions at the 2\u0027, 3\u0027-positions of purine and pyrimidine nucleosides proved to be regiospecific. In the pyrimidine series, the resulting 2\u0027, 3\u0027-olefins with a leaving group at the C-2\u0027 readily formed the corresponding 3\u0027-deoxy-2\u0027-keto-nucleosides, an entirely new class of bioorganic substances.\u003cbr/\u003eExploratory experiments aiming at base-sugar cyclization at the 4\u0027 -positions of nucleosides led to the N[3],C[4\u0027]-cyclization with concomitant decyclization of the base moiety in adenosine series, while in the pyrimidine series the first synthesis of O[2],C[4\u0027]-Crcyclonucleosides was achieved. Synthetic studies on the hitherto unexploited nitrogen-bridged cyclonucleosides were extensively conducted. The major topics cover (a) general synthesis of 2,3\u0027-imino and (substituted-imino) pyrimidine nucleosides,(b) regio and stereospecific synthesis of some reversed nucleosides through protected pyrimidine 6,5\u0027-N-cyclonucleosides, (c) general synthesis of purine 8,5\u0027-N-cyclonucleosides, (d) synthesis and chemistry of purine 8,2\u0027- and 8,3\u0027-long-bridged cyclonucleosides, (e) hydrolytic cleavage of the nitrogen bridge in the 2,2\u0027- and 2,3\u0027-(substituted-imino) pyrimidine nucleosides,(f) molecular rearrangements through the fission of the glycosidic bond in the general N-bridged cyclonucleosides, (g) strain-assisted hydrolysis of the nitrogen bridge of a pyrimidine multi-cyclic N-cyclonucleoside and (h) synthesis and chemistry of piperidine sugar uracil nucleosides. The final topic presents the synthesis and chemistry of 3-deoxy-3-nitro-hexopyranosyl nucleosides in both pyrimidine and purine series. The major results are stereoselective Michael addition reactions of various nucleophiles to the 3-nitro-2,3-unsaturated sugar nucleosides in both cases.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/memsenu.48.2.91", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "School of Engineering, Nagoya University", "subitem_publisher_language": "en"}]}, "item_9_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN（print）", "attribute_value_mlt": [{"subitem_source_identifier": "0919-0805", "subitem_source_identifier_type": "PISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Minamoto, Katsumaro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "101799", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "48-2-01.pdf", "filesize": [{"value": "3.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 3900000.0, "url": {"label": "48-2-01.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/30628/files/48-2-01.pdf"}, "version_id": "1ee99600-8746-4f05-a842-a0392f4b2b96"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Chemical modifications of natural nucleosides", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Chemical modifications of natural nucleosides", "subitem_title_language": "en"}]}, "item_type_id": "9", "owner": "1", "path": ["2533"], "permalink_uri": "https://doi.org/10.18999/memsenu.48.2.91", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-10-23"}, "publish_date": "2020-10-23", "publish_status": "0", "recid": "30628", "relation": {}, "relation_version_is_last": true, "title": ["Chemical modifications of natural nucleosides"], "weko_shared_id": -1}