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  1. B200 工学部/工学研究科
  2. B200b 紀要
  3. Memoirs of the School of Engineering, Nagoya University
  4. 47(1)

Crystallographic structural study of some hydrolases (hydrolytic enzymes) and their inhibitor proteins

https://doi.org/10.18999/memsenu.47.1.1
https://doi.org/10.18999/memsenu.47.1.1
9bcd1708-e421-454f-b1db-f95bf0c65daf
名前 / ファイル ライセンス アクション
47-1-01.pdf 47-1-01.pdf (5.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-10-23
タイトル
タイトル Crystallographic structural study of some hydrolases (hydrolytic enzymes) and their inhibitor proteins
言語 en
著者 Ashida, Tamaichi

× Ashida, Tamaichi

WEKO 101812

en Ashida, Tamaichi

Search repository
Yamane, Takashi

× Yamane, Takashi

WEKO 101813

en Yamane, Takashi

Search repository
Suzuki, Atsuo

× Suzuki, Atsuo

WEKO 101814

en Suzuki, Atsuo

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
抄録
内容記述 The X-ray crystallographic studies of the structures and functions of several hydrolases and proteinase inhibitor proteins have been carried out. Among Bowman-Birk type inhibitors the crystal of A-II from peanut, the (1:1) complex crystal between trypsin and AB-I from adzuki bean, and the (1:2) complex crystal of the same type inhibitor I-2 from wheat germ with trypsin have been studied at 2.3Å resolution, and the inhibition mechanism as well as the molecular structure of the BBI inhibitors were made clear. The structure of phospholipase A2 from venom of habu snake (Trimeresurus flavoviridis) was studied at the 1.5Å resolution, and the precise molecular structure, including the structures of catalytic triad, Asp-His-H[2]O, the "Ca-binding site", and several important water molecules for the activity of the enzyme were discussed. The effect of pH for the molecular structure of the enzyme was discussed with respect to its activity. The structures of other enzymes such as, an alkaline proteinase of subtilisin type from Bacillus sp. KSM-K16, trypsin of Streptomyces erythraeus, and thermostable bacterial α-amylase were also studied.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 School of Engineering, Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/memsenu.47.1.1
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0919-0805
書誌情報 en : Memoirs of the School of Engineering, Nagoya University

巻 47, 号 1, p. 1-45, 発行日 1995-10-31
著者版フラグ
値 publisher
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