{"created":"2021-03-01T06:39:21.557261+00:00","id":30979,"links":{},"metadata":{"_buckets":{"deposit":"610b3c4d-a914-4673-ada6-4c5297d2497a"},"_deposit":{"created_by":17,"id":"30979","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"30979"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00030979","sets":["499:508:509:2601"]},"author_link":["102433","102434","102435","102436","102437","102438","102439","102440","102441","102442","102443","102444","102445","102446","102447"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"733","bibliographicPageStart":"725","bibliographicVolumeNumber":"82","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The standard chemotherapy regimen for unresectable or recurrent biliary tract cancer is gemcitabine combined with cisplatin (GC). To evaluate the effectiveness and safety of chemotherapy in patients with unresectable or recurrent biliary tract cancer in the real world, we retrospectively analyzed the clinical courses of patients who underwent chemotherapy with GC from January 2015 to November 2019. Forty-eight patients underwent the GC regimen. One patient (2.1%) achieved a complete response, seven patients (14.6%) achieved a partial response, 26 patients (54.2) achieved stable disease, 11 patients (22.9%) achieved progressive disease, and 3 patients (6.3%) were not evaluable. The overall response rate was 16.7%. The median overall survival was 14.2 months (95% CI: 13.8–14.6), and the median progression-free survival was 7.7 months (95% CI: 4.2–11.2). Thirty-nine patients (81.3%) experienced grade 3 or higher severe adverse events as follows: 54.2% experienced neutropenia, 20.8% experienced anemia, 12.5% experienced thrombocytopenia and 20.8% experienced biliary tract infection. As a second-line chemotherapy, S-1 was used in seventeen patients, and stable disease was achieved in three patients (17.6%). The GC regimen for biliary tract cancer is effective and safe for unresectable or recurrent biliary tract cancer in routine clinical practice.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.82.4.725","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University Graduate School of Medicine, School of Medicine","subitem_publisher_language":"en"}]},"item_9_relation_43":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/824.html ","subitem_relation_type_select":"URI"}}]},"item_9_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International","subitem_rights_language":"en","subitem_rights_resource":"http://creativecommons.org/licenses/by-nc-nd/4.0/"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Maeda, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102433","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ebata, Tomoki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102434","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimokata, Tomoya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102435","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsuoka, Ayumu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102436","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inada-Inoue, Megumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102437","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Morita, Sachi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takano, Yuko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Urakawa, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miyai, Yuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugishita, Mihoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102442","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mitsuma, Ayako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102443","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ando, Masahiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mizuno, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102445","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagino, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102446","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ando, Yuichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102447","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-26"}],"displaytype":"detail","filename":"13_Maeda-2.pdf","filesize":[{"value":"7.3 MB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"label":"13_Maeda-2.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/30979/files/13_Maeda-2.pdf"},"version_id":"794ba97f-3a38-4a54-bff0-3dfe0d61fbd5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"biliary tract cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"cisplatin","subitem_subject_scheme":"Other"},{"subitem_subject":"gemcitabine","subitem_subject_scheme":"Other"},{"subitem_subject":"S-1","subitem_subject_scheme":"Other"},{"subitem_subject":"cholangiocarcinoma","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Chemotherapy for biliary tract cancer: real-world experience in a single institute","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Chemotherapy for biliary tract cancer: real-world experience in a single institute","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["2601"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-11-26"},"publish_date":"2020-11-26","publish_status":"0","recid":"30979","relation_version_is_last":true,"title":["Chemotherapy for biliary tract cancer: real-world experience in a single institute"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T02:45:05.294947+00:00"}