{"created":"2021-03-01T06:39:24.369605+00:00","id":31023,"links":{},"metadata":{"_buckets":{"deposit":"3b2bbb94-aed0-42a0-86c5-66689f423abb"},"_deposit":{"id":"31023","owners":[],"pid":{"revision_id":0,"type":"depid","value":"31023"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00031023","sets":["2081:2082:2083"]},"author_link":["102588"],"item_10_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-08","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"48","bibliographicPageStart":"42","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"Current Opinion in Structural Biology","bibliographic_titleLang":"en"}]}]},"item_10_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Regulating intercellular communication is essential for multicellular organisms. Gap junction channels are the major components mediating this function, but the molecular mechanisms underlying their opening and closing remain unclear. Single-particle cryo-electron microscopy (cryo-EM) is a powerful tool for investigating high-resolution protein structures that are difficult to crystallize, such as gap junction channels. Membrane protein structures are often determined in a detergent solubilized form, but lipid bilayers provide a near native environment for structural analysis. This review focuses on recent reports of gap junction channel structures visualized by cryo-EM. An overview of the differences observed in gap junction channel structures in the presence and absence of lipids is described, which may contribute to elucidating the regulation mechanisms of gap junction channel function.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"ファイル公開：2021-08-01","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.sbi.2020.03.008","subitem_relation_type_select":"DOI"}}]},"item_10_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_10_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_10_source_id_61":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0959-440X","subitem_source_identifier_type":"PISSN"}]},"item_1615787544753":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oshima, Atsunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"102588","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-08-01"}],"displaytype":"detail","filename":"Oshima_2020COSBT.pdf","filesize":[{"value":"348.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Oshima_2020COSBT","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/31023/files/Oshima_2020COSBT.pdf"},"version_id":"f7e87d3d-114a-40e9-89f1-17ec0006857f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Structural insights into gap junction channels boosted by cryo-EM","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Structural insights into gap junction channels boosted by cryo-EM","subitem_title_language":"en"}]},"item_type_id":"10","owner":"1","path":["2083"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-12-16"},"publish_date":"2020-12-16","publish_status":"0","recid":"31023","relation_version_is_last":true,"title":["Structural insights into gap junction channels boosted by cryo-EM"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-16T04:30:25.093053+00:00"}