@article{oai:nagoya.repo.nii.ac.jp:00031058,
 author = {Nagai, Keisuke and Mori, Yoshinao and Ishikawa, Shin and Furuta, Tomoyuki and Gamuyao, Rico and Niimi, Yoko and Hobo, Tokunori and Fukuda, Moyuri and Kojima, Mikiko and Takebayashi, Yumiko and Fukushima, Atsushi and Himuro, Yasuyo and Kobayashi, Masatomo and Ackley, Wataru and Hisano, Hiroshi and Sato, Kazuhiro and Yoshida, Aya and Wu, Jianzhong and Sakakibara, Hitoshi and Sato, Yutaka and Tsuji, Hiroyuki and Akagi, Takashi and Ashikari, Motoyuki},
 issue = {7819},
 journal = {Nature},
 month = {Aug},
 note = {The size of plants is largely determined by growth of the stem. Stem elongation is stimulated by gibberellic acid1,2,3. Here we show that internode stem elongation in rice is regulated antagonistically by an ‘accelerator’ and a ‘decelerator’ in concert with gibberellic acid. Expression of a gene we name ACCELERATOR OF INTERNODE ELONGATION 1 (ACE1), which encodes a protein of unknown function, confers cells of the intercalary meristematic region with the competence for cell division, leading to internode elongation in the presence of gibberellic acid. By contrast, upregulation of DECELERATOR OF INTERNODE ELONGATION 1 (DEC1), which encodes a zinc-finger transcription factor, suppresses internode elongation, whereas downregulation of DEC1 allows internode elongation. We also show that the mechanism of internode elongation that is mediated by ACE1 and DEC1 is conserved in the Gramineae family. Furthermore, an analysis of genetic diversity suggests that mutations in ACE1 and DEC1 have historically contributed to the selection of shorter plants in domesticated populations of rice to increase their resistance to lodging, and of taller plants in wild species of rice for adaptation to growth in deep water. Our identification of these antagonistic regulatory factors enhances our understanding of the gibberellic acid response as an additional mechanism that regulates internode elongation and environmental fitness, beyond biosynthesis and gibberellic acid signal transduction., ファイル公開：2021/02/06},
 pages = {109--114},
 title = {Antagonistic regulation of the gibberellic acid response during stem growth in rice},
 volume = {584},
 year = {2020}
}