@article{oai:nagoya.repo.nii.ac.jp:00031323, author = {Zheng, Shaofeng and Masuda, Takahiko and Matsunaga, Masahiro and Noguchi, Yasuki and Ohtsubo, Yohsuke and Yamasue, Hidenori and Ishii, Keiko}, journal = {Psychoneuroendocrinology}, month = {Nov}, note = {Early-life environments have been associated with various social behaviors, including trust, in late adolescence and adulthood. Given that the oxytocin receptor gene polymorphism (OXTR rs53576) moderates the impact of childhood experience on social behaviors, in the present study, we examined the main effect of childhood adversity through a self-report measure and its interactions with OXTR rs53576 on general trust among 203 Japanese and 200 European Canadian undergraduate students. After controlling for the effect of culture, the results indicated that childhood adversity had a negative association with general trust, and that OXTR rs53576 moderated the impact of childhood adversity on general trust. Specifically, the negative association between childhood adversity and general trust is only significant among homozygote A-allele carriers. These findings demonstrated that OXTR rs53576 moderated the relations between childhood experiences and social functioning in early adulthood., ファイル公開:2021-11-01}, title = {Oxytocin Receptor Gene (OXTR) and Childhood Adversity Influence Trust}, volume = {121}, year = {2020} }