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Acute myeloid leukemia in the elderly : 159 Nagoya case studies
https://doi.org/10.18999/nagjms.62.3-4.135
https://doi.org/10.18999/nagjms.62.3-4.135254016af-9565-4fe2-91bb-7312bf8de211
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
nj6237.pdf (68.9 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-02-03 | |||||
| タイトル | ||||||
| タイトル | Acute myeloid leukemia in the elderly : 159 Nagoya case studies | |||||
| 言語 | en | |||||
| 著者 |
Nagura, Eiichi
× Nagura, Eiichi× Minami, Saburo× Nagata, Koichiro× Morishita, Yoshihisa× Takeyama, Hideo× Sao, Hiroshi× Suzuki, Hisamitsu× Naoe, Tomoki× Yokomaku, Shozo× Mizuno, Harumitsu× Murase, Takuhei× Hirabayashi, Noriyuki× Takeo, Takaaki× Tanimoto, Mitsune× Kawashima, Kohei× Saito, Hidehiko |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Elderly leukemia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | elderly AML | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | De novo AML | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | AML evolved from MDS | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To obtain background information on elderly acute myeloid leukemia (AML), unselected data covering 159 patients aged 60 years or over with AML from 14 hospitals in Nagoya, Japan was analyzed retrospectively. Among these patients, 119 had de novo acute AML, 32 had AML which evolved from myelodysplastic syndrome (MDS-AML), and 8 had other types of leukemia. The survey showed that MDS-AML tended to be more prevalent in patients aged 70 years and older and that MDS-AML showed a significantly more severe degree of leukopenia and anemia than de novo AML. MDS-AML also showed a significantly lower complete remission (CR) rate than that of de novo AML [6.9% (2/29) vs 58.3% (67/11), P < 0.01] and significantly shorter survival times than those of de novo AML [median: 3.6 months vs 9.6 months, P < 0.01 (generalized Wilcoxon test; GW]. In de novo AML, the proportion of patients treated with conventional therapy (CT group) decreased significantly, and that of those with attenuated therapy (AT group) increased significantly as age elevated (P < 0.01). The CT group showed a significantly higher CR rate (65.4% vs 41.2%, P < 0.05) and a significantly longer survival period than those of the AT group [median: 11.6 months vs 4.8 months, P < 0.05 (GW)]. Overall survival rates of the older age groups became significantly shorter with aging [P < 0.01 (GW)]. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.62.3-4.135 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 62, 号 3-4, p. 135-144, 発行日 1999-11 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/5348 | |||||
| 識別子タイプ | HDL | |||||
