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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 62(3-4)

Acute myeloid leukemia in the elderly : 159 Nagoya case studies

https://doi.org/10.18999/nagjms.62.3-4.135
https://doi.org/10.18999/nagjms.62.3-4.135
254016af-9565-4fe2-91bb-7312bf8de211
名前 / ファイル ライセンス アクション
nj6237.pdf nj6237.pdf (68.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2006-02-03
タイトル
タイトル Acute myeloid leukemia in the elderly : 159 Nagoya case studies
著者 Nagura, Eiichi

× Nagura, Eiichi

WEKO 9958

Nagura, Eiichi

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Minami, Saburo

× Minami, Saburo

WEKO 9959

Minami, Saburo

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Nagata, Koichiro

× Nagata, Koichiro

WEKO 9960

Nagata, Koichiro

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Morishita, Yoshihisa

× Morishita, Yoshihisa

WEKO 9961

Morishita, Yoshihisa

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Takeyama, Hideo

× Takeyama, Hideo

WEKO 9962

Takeyama, Hideo

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Sao, Hiroshi

× Sao, Hiroshi

WEKO 9963

Sao, Hiroshi

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Suzuki, Hisamitsu

× Suzuki, Hisamitsu

WEKO 9964

Suzuki, Hisamitsu

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Naoe, Tomoki

× Naoe, Tomoki

WEKO 9965

Naoe, Tomoki

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Yokomaku, Shozo

× Yokomaku, Shozo

WEKO 9966

Yokomaku, Shozo

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Mizuno, Harumitsu

× Mizuno, Harumitsu

WEKO 9967

Mizuno, Harumitsu

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Murase, Takuhei

× Murase, Takuhei

WEKO 9968

Murase, Takuhei

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Hirabayashi, Noriyuki

× Hirabayashi, Noriyuki

WEKO 9969

Hirabayashi, Noriyuki

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Takeo, Takaaki

× Takeo, Takaaki

WEKO 9970

Takeo, Takaaki

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Tanimoto, Mitsune

× Tanimoto, Mitsune

WEKO 9971

Tanimoto, Mitsune

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Kawashima, Kohei

× Kawashima, Kohei

WEKO 9972

Kawashima, Kohei

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Saito, Hidehiko

× Saito, Hidehiko

WEKO 9973

Saito, Hidehiko

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キーワード
主題Scheme Other
主題 Elderly leukemia
キーワード
主題Scheme Other
主題 elderly AML
キーワード
主題Scheme Other
主題 De novo AML
キーワード
主題Scheme Other
主題 AML evolved from MDS
抄録
内容記述 To obtain background information on elderly acute myeloid leukemia (AML), unselected data covering 159 patients aged 60 years or over with AML from 14 hospitals in Nagoya, Japan was analyzed retrospectively. Among these patients, 119 had de novo acute AML, 32 had AML which evolved from myelodysplastic syndrome (MDS-AML), and 8 had other types of leukemia. The survey showed that MDS-AML tended to be more prevalent in patients aged 70 years and older and that MDS-AML showed a significantly more severe degree of leukopenia and anemia than de novo AML. MDS-AML also showed a significantly lower complete remission (CR) rate than that of de novo AML [6.9% (2/29) vs 58.3% (67/11), P < 0.01] and significantly shorter survival times than those of de novo AML [median: 3.6 months vs 9.6 months, P < 0.01 (generalized Wilcoxon test; GW]. In de novo AML, the proportion of patients treated with conventional therapy (CT group) decreased significantly, and that of those with attenuated therapy (AT group) increased significantly as age elevated (P < 0.01). The CT group showed a significantly higher CR rate (65.4% vs 41.2%, P < 0.05) and a significantly longer survival period than those of the AT group [median: 11.6 months vs 4.8 months, P < 0.05 (GW)]. Overall survival rates of the older age groups became significantly shorter with aging [P < 0.01 (GW)].
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.62.3-4.135
ID登録タイプ JaLC
書誌情報 Nagoya Journal of Medical Science

巻 62, 号 3-4, p. 135-144, 発行日 1999-11
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/5348
識別子タイプ HDL
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