@article{oai:nagoya.repo.nii.ac.jp:00003946, author = {Ikoma, Masanobu and Baba, Reizo and Mochiduki, Shinsuke and Iwagaki, Suketsune}, issue = {1-2}, journal = {Nagoya Journal of Medical Science}, month = {May}, note = {Background: The effect of exercise protocol on the slope of the relationship between minute ventilation and carbon dioxide production (△VE/△VCO2) has not fully been studied. Methods: Twenty-five healthy volunteers performed two sessions of incremental bicycle exercise, one with a rapidly increasing staged (RIS: 25W every minute) protocol and another with a slowly increasing staged (SIS: 25W every 3 minutes) protocol to calculate the △VE/△VCO2. Six of the subjects also participated in sessions of steady state exercise (SSE) test various work rates. Results: The △VE/△VCO2 was significantly lower when the RIS protocol was used than when the SIS protocol was used (23.3±2.3 vs. 24.9±8, p<0.001). Data from the subjects who also underwent SSE sessions revealed that the △VE/△VCO2 from the SSE protocols was greater than that from the RIS protocol and identical with that from the SIS protocol (25.1±7, 20.6±7, and 24.0±2.7, respectively, p<0.05), while arterial partial pressure of carbon dioxide during exercise was not different between the protocols (43.0±3.3, 39.9±1, and 40.8±2.6, respectively, n.s.). Conclusions: Care must be taken in the interpretation of the values of △VE/△VCO2, as they are influenced by the difference in exercise protocol.}, pages = {37--42}, title = {Effect of exercise testing protocol on the relationship between minute ventilation and carbon dioxide production}, volume = {65}, year = {2002} }