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Angiogenesis and vasculogenesis for therapeutic neovascularization
https://doi.org/10.18999/nagjms.66.1-2.1
https://doi.org/10.18999/nagjms.66.1-2.144d37431-e788-4f26-bf48-e97f2db26270
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-02-09 | |||||
タイトル | ||||||
タイトル | Angiogenesis and vasculogenesis for therapeutic neovascularization | |||||
著者 |
Murohara, Toyoaki
× Murohara, Toyoaki |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | Angiogenesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Vasculogenesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ischemia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Progenitor Cell | |||||
抄録 | ||||||
内容記述 | Peripheral blood of adult species contains endothelial progenitor cells (EPCs) that participate in neovascularization, consistent with postnatal vasculogenesis. EPCs can be isolated not only from peripheral blood but also from bone marrow and human umbilical cord blood. In vitro culture-expanded EPCs participate in endothelial network formation (capillary formation) in vitro, and transplanted EPCs have been incorporated into sites of active neovascularization. For example, transplanted human EPCs formed capillaries among preserved skeletal myocytes in the ischemic hindlimb of athymic nude rats in vivo. Furthermore, transplantation of EPCs functionally augmented neovascularization in response to hindlimb ischemia. Thus, transplantation of EPCs may become a useful strategy to modulate postnatal neovascularization. |
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内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.66.1-2.1 | |||||
ID登録タイプ | JaLC | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 66, 号 1-2, p. 1-7, 発行日 2003-05 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/5392 | |||||
識別子タイプ | HDL |