{"created":"2021-03-01T06:10:26.469453+00:00","id":3960,"links":{},"metadata":{"_buckets":{"deposit":"c73234eb-defd-4974-abff-e9c12ca5885e"},"_deposit":{"created_by":17,"id":"3960","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"3960"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00003960","sets":["499:508:509:517"]},"author_link":["10131","10132","10133"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"93","bibliographicPageStart":"87","bibliographicVolumeNumber":"66","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Vasopressin has an important role in water metabolism and its impairment induces some clinical disorders such as diabetes insipidus or syndrome of inappropriate antidiuresis (SIAD). SIAD is caused by the overproduction of vasopressin which induces diluting hyponatremia. The accurate diagnosis and appropriate therapy have not settled up to date because its pathophysiology is very complicated. It is meaningful to develop a rat model of SIAD in which human vasopressin gene is overexpressed in order to analyze pathophysiological changes. Several models transgenic for vasopressin including us had been generated. The transgenic rats provide a useful model to investigate various pathophysiological changes resulting from the oversecretion of vasopressin. Some interesting results based on these animal models are reviewed.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/5393"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.66.3-4.87","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_9_text_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_text_value":"application/pdf"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oiso, Yutaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"10131","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagasaki, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"10132","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokoi, Hisashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"10133","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-19"}],"displaytype":"detail","filename":"nj6632.pdf","filesize":[{"value":"50.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nj6632.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/3960/files/nj6632.pdf"},"version_id":"b29d89f9-992b-4cb9-864c-1e40d0cbd6e3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"vasopressin","subitem_subject_scheme":"Other"},{"subitem_subject":"V2 receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"transgenic rat","subitem_subject_scheme":"Other"},{"subitem_subject":"downregulation","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Transgenic rat models of vasopressin overexpression","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Transgenic rat models of vasopressin overexpression","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["517"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2006-02-10"},"publish_date":"2006-02-10","publish_status":"0","recid":"3960","relation_version_is_last":true,"title":["Transgenic rat models of vasopressin overexpression"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T06:43:08.574277+00:00"}