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Elective neck irradiation on ipsilateral side in patients with early tongue cancer for high-risk group with late cervical lymph node metastasis
https://doi.org/10.18999/nagjms.68.1-2.53
https://doi.org/10.18999/nagjms.68.1-2.53122aa283-35e0-4453-8c41-f10e6cab6782
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-03-01 | |||||
タイトル | ||||||
タイトル | Elective neck irradiation on ipsilateral side in patients with early tongue cancer for high-risk group with late cervical lymph node metastasis | |||||
著者 |
Ito, Yoshiyuki
× Ito, Yoshiyuki× Fuwa, Nobukazu× Kikuchi, Yuzo× Yokoi, Norio× Hamajima, Nobuyuki× Morita, Kozo× 伊藤, 義之× 濱嶋, 信之 |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tongue cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Elective neck irradiation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Brachytherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cervical lymph node metastasis | |||||
抄録 | ||||||
内容記述 | A prospective study was performed to assess the effi cacy of elective neck irradiation (ENI) on the ipsilateral side in patients with early tongue cancer among a high-risk group with late cervical lymph node metastasis. Patients in the high-risk group had T2-tumors, excluding superfi cials or T1-tumors >=19 mm in maximal diameter with invasion or ulcer. Between February 1989 and October 1997, 70 patients with tongue cancer of Stages I and II were enrolled in the present study (ENI group: 31, non-ENI group: 39). In a combination therapy of external beam irradiation and brachytherapy, the standard dose of interstitial brachytherapy for primary tumors was approximately 60 Gy. Irradiation was initiated with a 9-MeV electron beam at a dose of 50 Gy on the ipsilateral side of the neck only when the day of brachytherapy approached. Three patients (9.7%) in the ENI group had neck lymph node metastasis as did 5 (12.8%) in the non-ENI group (p= 0.684). In patients with ulceration, the incidence of subsequent lymph node metastasis was signifi cantly higher (p=0.029). Neck lymph node metastasis occurred in 2 (16.7%) of 12 patients with ulcers in the ENI group and in 2 (66.7%) of 3 with ulcers in the non-ENI group. Although we could not demonstrate the signifi cant effi cacy of ENI in the high-risk group in this study, ENI decreased the neck lymph node metastasis. In addition, our results suggested that ENI particularly inhibits cervical lymph node metastasis in tongue tumor patients with ulcers. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.68.1-2.53 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00277622 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 68, 号 1-2, p. 53-62, 発行日 2006-01 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/6133 | |||||
識別子タイプ | HDL |