@phdthesis{oai:nagoya.repo.nii.ac.jp:00004983,
 author = {Shimada, Kiyoshi and 島田, 清司},
 month = {May},
 note = {The electroencephalogram (EEG) of the chicken hypothalamus was recorded under the influence of repetitive photic stimulation, while thyroid activity was assessed by determining blood protein bound 131 I levels in sequential samles. Samples. EEG waves in regions examined were distinctly entrained with a flicker frequency. The blood PB 131 I level was increased by 20 min photic stimulation of 3 cps and was decreased by 12 cps flicker, while 24 cps flicker exerted no effect on thyroid function. Blood PB131 I level was increased by TSH and TRH treatments. These results indicate that the frequencyspecific effects are mediated by changes in the hypothalamo-pituitary function. Blood PB131 I was determined in chickens which were exposed to cold and photic stimulation. Slight increase in thyroid activity was resulted from 9 cps flicker in chickens at a room temperature. When the birds were exposed to cold only, a slow but significant elevation in PB131 I levels was resulted. On the other hand, the birds exposed to cold did not indicate any sign of increase in PB131 I when 9 cps flicker was delivered to them. The results suggest that this photic stimulation modifies the responsiveness of the hypothalamo-pituitary function to cold exposure. In the third experiment concentrations of corticosterone, immunoreactive thyrotropin (TSH) and growthhormone (GH) in plasma were measured 25 min after repetitive photic stimulation of 3,9,15 and 24 cps in rats. Photically evoked responses were recorded from midbrain reticular formation, amygdala, hippocampus and medial basal hypothalamus. The patterns of evoked responses at all the points examined were altered by the changes in stimulation frequency, forming the specific rhythmic patterns. Mean corticosterone concentration was increased but no significant change was demonstrable in mean TSH and GH levels. The results suggest that corticosterone concentration is dependent on the electrophysiological state of the CNS which is characterized by the specific rhythmic evoked responses., 名古屋大学博士学位論文 学位の種類:農学博士 (課程) 学位授与年月日:昭和50年5月26日},
 school = {名古屋大学, NAGOYA University},
 title = {Studies on the Role of Artificially Induced EEG Changes in the Regulation of Anterior Pituitary Functions},
 year = {1975}
}