@article{oai:nagoya.repo.nii.ac.jp:00005950, author = {Yu, Jin and Koda, Hisashi and Mizumura, Kazue}, journal = {Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University}, month = {Dec}, note = {The aim of this study was to examine visceral afferent characteristics in rats and investigate the effect of zaltoprofen on their responses to bradykinin. Single fiber recordings were performed using rat spermatic nerve preparations in vitro. More than 90% of units tested with thermal, mechanical and chemical (bradykinin, pH, etc) stimulations responded to all of them, and thus were identified to be polymodal receptors. The responses of these receptors to bradykinin (10^-9 M to 10^-5 M) showed concentration dependency. There were almost no fibers with receptive fields on the testis, unlike the canine and feline spermatic afferents. In addition, zaltoprofen (10^-5 M), a non-steroidal anti-inflammatory drug, suppressed the bradykinin response of these receptors., 国立情報学研究所で電子化したコンテンツを使用している。}, pages = {22--25}, title = {Rat Visceral Polymodal Receptors and Suppression by Zaltoprofen of Their Responses to Bradykinin In Vitro}, volume = {47}, year = {2003} }