{"created":"2021-03-01T06:12:32.728661+00:00","id":5958,"links":{},"metadata":{"_buckets":{"deposit":"f6e81f80-3b3f-4e86-9cf9-49659b9052a1"},"_deposit":{"id":"5958","owners":[],"pid":{"revision_id":0,"type":"depid","value":"5958"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00005958","sets":["329:333:334:737"]},"author_link":["15858","15859","15860","15861","15862","15863","15864","15865"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"38","bibliographicPageStart":"37","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Gap junction remodeling have been reported in various types of heart disease. Information available for the gap junction remodeling after myocardial infarction is still limited. In the present study, we investigated mRNA expression of connexin 43 (Cx43), major protein of gap junction channels in compensated hypertrophied interventricular septum (IVS) after myocardial infarction (MI) in mice by using a real time quantitative PCR expression. Cx43 mRNA expression in the interventricular septum of MI mouse was significantly decreased by 2 fold (813.7±252.6 molecules / 10^5 GAPDH molecules) compared to non-operated control (1628.9±180.9) and sham-operated mice (2051.9±169.8). There was no significant difference in Cx43 mRNA between control and sham groups. Down-regulation of Cx43 mRNA in compensated hypertrophied myocardium could be involved in the arrythmogenic substrate in the heart after MI.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"国立情報学研究所で電子化したコンテンツを使用している。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/7571"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/envm.47.37","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Research Institute of Environmental Medicine, Nagoya University","subitem_publisher_language":"en"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0287-0517","subitem_source_identifier_type":"PISSN"}]},"item_9_text_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_text_value":"application/pdf"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takemura, Haruki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15858","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasui, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15859","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Niwa, Noriko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15860","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hojo, Mayumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15861","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Horiba, Mitsuru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15862","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Lee, Jong-Kook","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15863","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yuichi, Ueda","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kodama, Itsuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15865","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-19"}],"displaytype":"detail","filename":"37-38.pdf","filesize":[{"value":"209.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"37-38.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/5958/files/37-38.pdf"},"version_id":"40859036-c57d-4940-8917-e36a5e0f1746"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gap junction","subitem_subject_scheme":"Other"},{"subitem_subject":"connexin43","subitem_subject_scheme":"Other"},{"subitem_subject":"mouse","subitem_subject_scheme":"Other"},{"subitem_subject":"hypertrophy","subitem_subject_scheme":"Other"},{"subitem_subject":"myocardial infarction","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction","subitem_title_language":"en"}]},"item_type_id":"9","owner":"1","path":["737"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-04-05"},"publish_date":"2007-04-05","publish_status":"0","recid":"5958","relation_version_is_last":true,"title":["Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-26T06:20:19.877514+00:00"}