@article{oai:nagoya.repo.nii.ac.jp:00005988,
 author = {Iwase, Satoshi and Fu, Qi and Morimoto, Eiichi and Takada, Hiroki and Kamiya, Atsunori and Michikami, Daisaku and Kawanokuchi, Jun and Shiozawa, Tomoki and Hirayanagi, Kaname and Iwasaki, Ken-ichi and Yajima, Kazuyoshi and Mano, Tadaaki},
 journal = {Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University},
 month = {Dec},
 note = {To test the effectiveness of centrifuge-induced artificial gravity with ergometric exercise, 12 healthy young men (20.7±1.9yrs) were exposed to simulated microgravity for 14 days of-6°head-down bedrest. Half the subjects were randomly selected and loaded 1.2 G artificial gravity with 60 W (four out of six subjects) or 40 W (two out of six subjects) of ergometric workload on days 1,2,3,5,7,9,11.12,13,14(CM group). The rest of the subjects served as the control. Anti-G score, defined as the G-load x running time to the endpoint, was significantly elongated by the load of the centrifuge-ergometer.Plasma volume loss was suppressed(-5.0±2.4 vs-16.4±1.9%),and fluid volume shift was prevented by the countermeasure load. Elevated heart rate and muscle sympathetic nerve activity after bedrest were counteracted, and exaggerated response to head-up tilt was also suppressed. Centrifuge-induced artificial gravity with exercise is effective in preventing cardiovascular deconditioning due to microgravity exposure, however, as effective and appropriate regimen (magnitude of G-load and exercise workload)should be determined in future studies., 国立情報学研究所で電子化したコンテンツを使用している。},
 pages = {76--80},
 title = {Effectiveness of Centrifuge-induced Artificial Gravity with Ergometric Exercise as a Countermeasure during Simulated Microgravity Exposure in Humans},
 volume = {47},
 year = {2003}
}