@article{oai:nagoya.repo.nii.ac.jp:00007073, author = {HASEGAWA, Takuya and MATSUURA, Hirotaka and INAGAKI, Kazumi and HARAGUCHI, Hiroki}, issue = {1}, journal = {Analytical Sciences}, month = {Jul}, note = {The major-to-ultratrace elements in human bone-marrow fluid were determined by ICP-AES (inductively coupled plasma atomic emission spectrometry), and ICP-MS (inductively coupled plasma mass spectrometry). The bone-marrow fluid sample was centrifuged prior to acid digestion to exclude the bone piece from bone marrow, and then digested with nitric acid. As a result, 20 elements could e determined over the concentration range from 1610 μg g^-1 for Na to 0.00043 μg g^-1 for W. It was found that Fe, Zn and Sb were enriched by ca. 264-, 7- and 15-fold, respectively, in bone-marrow fluid, compared to those in human blood serum. Alkali metals (K, Rb, Cs), except for Na, were also significantly enriched in bone-marrow fluid. Furthermore, the concentrations of various elements, such as Fe, P, Al, Zn, Cu, Se, Zr, Sn, Ag and W, were significantly higher than those in open seawater.}, pages = {147--150}, title = {Major-to-Ultratrace Elements in Bone-Marrow Fluid as Determined by ICP-AES and ICP-MS}, volume = {19}, year = {2003} }