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  1. B200 工学部/工学研究科
  2. B200a 雑誌掲載論文
  3. 学術雑誌

Speciation of Drugs in Blood Serum by Surfactant-Mediated HPLC/ICP-MS with Direct Sample Injection

http://hdl.handle.net/2237/8758
http://hdl.handle.net/2237/8758
62dcd283-2d28-4681-8f29-43c4a1ab4016
名前 / ファイル ライセンス アクション
v17-S_i37-i40.pdf v17-S_i37-i40.pdf (67.9 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-09-18
タイトル
タイトル Speciation of Drugs in Blood Serum by Surfactant-Mediated HPLC/ICP-MS with Direct Sample Injection
言語 en
著者 HARAGUCHI, Hiroki

× HARAGUCHI, Hiroki

WEKO 19128

en HARAGUCHI, Hiroki

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OHSHIMA, Tomomi

× OHSHIMA, Tomomi

WEKO 19129

en OHSHIMA, Tomomi

Search repository
MATSUURA, Hirotaka

× MATSUURA, Hirotaka

WEKO 19130

en MATSUURA, Hirotaka

Search repository
HASEGAWA, Takuya

× HASEGAWA, Takuya

WEKO 19131

en HASEGAWA, Takuya

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
抄録
内容記述 Speciation of cisplatin (CDDP; cis-diamminedichloroplatinum(Ⅱ)), anti-cancer drug, in human blood serum has been carried out by surfactant- mediated HPLC/ICP-MS. In the surfactant-mediated HPLC, an ODS (octadesylsilica) column coated with CHAPS (3-[3-cholamidopropyl]-dimethylammonio) propanesulfonic acid), which is a zwitterionic surfactant obtained as a bile acid derivative, was employed as a stationary phase, and ICP-MS was used for detection of 195Pt. Since the present surfactant-mediated stationary phase had the characteristics of rapid separation of large and small molecules with capability of direct sample injection even for blood serum without any pretreatment, CDDP and its complexes with cysteine and albumin in addition to some hydrolysis-type complexes were found in human blood serum.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 Proceedings of IUPAC International Congress on Analytical Sciences 2001 (ICAS 2001)
言語 en
内容記述タイプ Other
出版者
言語 ja
出版者 日本分析化学会
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.14891/analscisp.17icas.0.i37.0
ISSN
収録物識別子タイプ PISSN
収録物識別子 0910-6340
書誌情報 en : Analytical Sciences

巻 17, 号 sup, p. i37-i40, 発行日 2001
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/8758
識別子タイプ HDL
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