ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "c89e94f8-4554-4cbd-816c-1966243b6e19"}, "_deposit": {"id": "7248", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "7248"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00007248", "sets": ["894"]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-07", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "68", "bibliographicPageStart": "61", "bibliographicVolumeNumber": "4", "bibliographic_titles": [{"bibliographic_title": "農学国際協力"}]}]}, "item_9_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Lipids (edible fats and oils, phospholipids and glycolipids, etc) are one of major important food resources, in addition to carbohydrate (starch, sugar, etc.) and protein resources. Edible fats and oils are produced mostly from agricultural products such as plant seeds and animals. Animal-derived fats and oils are also utilized as energy sources in human nutrition. Fish oils have some functional fatty acids categorized as n-3 polyunsaturated fatty acids (PUFA) with 5 and 6 unconjugated methene double bonds. Phospholipids are utilized as food and cosmetic emulsifier (pure grade), and animal feed (crude). Enzymes, which are involved as catalysts (biocatalysts) in all metabolisms and biochemical reactions in living cells, are very tightly connected with all life phenomena. Two novel engineering disciplines relating to effective enzyme utilization have emerged in the late 20th century: enzyme engineering and protein engineering. Enzyme engineering is a branch of bioprocess engineering devoted to increasing efficacy of enzyme utilization as biocatalysts for various bioconversions. Protein engineering is one of major branches of biomolecular engineering, aiming at creation of enzymes of better nature through various genetic engineering techniques such as site-directed mutagenesis, error-prone PCR, DNA shuffling, molecular evolution technique, etc. Natural lipids are a mixture of hundreds or thousands of triacylglycerols when looked at from the viewpoint of organic chemistry. Recently, the so-called ‘structured lipids’ have attracted much attention. In the strictest sense, the structured lipids are those having definite chemical structure. From a number of clinical experiments in lipids nutrition science, structured triacylglycerols (sTAG) have been shown to confer various enhanced nutritional values so that they are useful as functional foods or nutritional supplements. Taking advantage of enzyme’s properties, the author and his co-researchers have been studying enzyme engineering for lipids bioconversions for many years. Recent studies showed success in making feasible the industrial production of 1,3-dioctanoyl -2-docosahexaenoyl-sn-glycerol by the action of immobilized lipases following a two-step process, i.e. ethanolysis of fish oil by immobilized Candida antarctica lipase followed by re-esterification of the resulting 2-monoacylglycerol with n-octanoic acid by immobilized Rhizomuco miehei lipase in neat system. Phosphatidylserine (PS), which is one of structured phospholipids (sPL), is found neither in soy- nor in egg-lecithin, but is contained highly in mammalian cerebral cortex, and is claimed to be effective for Age-Associated Memory Impairment (AAMI). Recently, an efficient high-yield synthesis technique of PS from lecithin by the transphophatidylation action of Streptomyces phospholipase D in non-solvent system has been developed.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/8930"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/jouica.4.61", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "名古屋大学農学国際教育協力研究センター"}]}, "item_9_relation_43": {"attribute_name": "異版である", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://iccae.agr.nagoya-u.ac.jp/publication/bulletin/pdf/body4.pdf", "subitem_relation_type_select": "URI"}}]}, "item_9_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN(print)", "attribute_value_mlt": [{"subitem_source_identifier": "1347-5096", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "YAMANE, Tsuneo"}], "nameIdentifiers": [{"nameIdentifier": "19949", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "61-68.pdf", "filesize": [{"value": "434.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 434200.0, "url": {"label": "61-68.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/7248/files/61-68.pdf"}, "version_id": "8122d627-5a8e-4da6-bc3f-bc6b82e5195f"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Enzyme Engineering for Lipids", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Enzyme Engineering for Lipids"}]}, "item_type_id": "9", "owner": "1", "path": ["894"], "permalink_uri": "https://doi.org/10.18999/jouica.4.61", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-10-29"}, "publish_date": "2007-10-29", "publish_status": "0", "recid": "7248", "relation": {}, "relation_version_is_last": true, "title": ["Enzyme Engineering for Lipids"], "weko_shared_id": 3}
  1. H140 農学国際教育協力研究センター
  2. H140b 紀要
  3. 農学国際協力
  4. 4

Enzyme Engineering for Lipids

https://doi.org/10.18999/jouica.4.61
https://doi.org/10.18999/jouica.4.61
41997384-196b-44b7-bc57-bc8fb739fd34
名前 / ファイル ライセンス アクション
61-68.pdf 61-68.pdf (434.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-10-29
タイトル
タイトル Enzyme Engineering for Lipids
著者 YAMANE, Tsuneo

× YAMANE, Tsuneo

WEKO 19949

YAMANE, Tsuneo

Search repository
抄録
内容記述 Lipids (edible fats and oils, phospholipids and glycolipids, etc) are one of major important food resources, in addition to carbohydrate (starch, sugar, etc.) and protein resources. Edible fats and oils are produced mostly from agricultural products such as plant seeds and animals. Animal-derived fats and oils are also utilized as energy sources in human nutrition. Fish oils have some functional fatty acids categorized as n-3 polyunsaturated fatty acids (PUFA) with 5 and 6 unconjugated methene double bonds. Phospholipids are utilized as food and cosmetic emulsifier (pure grade), and animal feed (crude). Enzymes, which are involved as catalysts (biocatalysts) in all metabolisms and biochemical reactions in living cells, are very tightly connected with all life phenomena. Two novel engineering disciplines relating to effective enzyme utilization have emerged in the late 20th century: enzyme engineering and protein engineering. Enzyme engineering is a branch of bioprocess engineering devoted to increasing efficacy of enzyme utilization as biocatalysts for various bioconversions. Protein engineering is one of major branches of biomolecular engineering, aiming at creation of enzymes of better nature through various genetic engineering techniques such as site-directed mutagenesis, error-prone PCR, DNA shuffling, molecular evolution technique, etc. Natural lipids are a mixture of hundreds or thousands of triacylglycerols when looked at from the viewpoint of organic chemistry. Recently, the so-called ‘structured lipids’ have attracted much attention. In the strictest sense, the structured lipids are those having definite chemical structure. From a number of clinical experiments in lipids nutrition science, structured triacylglycerols (sTAG) have been shown to confer various enhanced nutritional values so that they are useful as functional foods or nutritional supplements. Taking advantage of enzyme’s properties, the author and his co-researchers have been studying enzyme engineering for lipids bioconversions for many years. Recent studies showed success in making feasible the industrial production of 1,3-dioctanoyl -2-docosahexaenoyl-sn-glycerol by the action of immobilized lipases following a two-step process, i.e. ethanolysis of fish oil by immobilized Candida antarctica lipase followed by re-esterification of the resulting 2-monoacylglycerol with n-octanoic acid by immobilized Rhizomuco miehei lipase in neat system. Phosphatidylserine (PS), which is one of structured phospholipids (sPL), is found neither in soy- nor in egg-lecithin, but is contained highly in mammalian cerebral cortex, and is claimed to be effective for Age-Associated Memory Impairment (AAMI). Recently, an efficient high-yield synthesis technique of PS from lecithin by the transphophatidylation action of Streptomyces phospholipase D in non-solvent system has been developed.
内容記述タイプ Abstract
出版者
出版者 名古屋大学農学国際教育協力研究センター
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/jouica.4.61
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://iccae.agr.nagoya-u.ac.jp/publication/bulletin/pdf/body4.pdf
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 1347-5096
書誌情報 農学国際協力

巻 4, p. 61-68, 発行日 2004-07
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/8930
識別子タイプ HDL
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 12:21:56.516135
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3