{"_buckets": {"deposit": "156dddf6-e90c-4a39-a6a3-10138f23caf1"}, "_deposit": {"id": "7568", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "7568"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00007568", "sets": ["667"]}, "author_link": ["21318", "21319", "21320", "21321", "21322", "21323"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "201", "bibliographicPageStart": "198", "bibliographicVolumeNumber": "416", "bibliographic_titles": [{"bibliographic_title": "Neuroscience Letters", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Food intake in chickens is regulated in a manner similar to that in mammals. Corticotropin-releasing factor (CRF), which increases the plasma corticosterone concentration, plays an important role as a mediator of many appetite-suppressive peptides in the central nervous system in both species. Central administration of glucagon suppresses food intake in rats. However, the anorexigenic action of glucagon in chicks has not yet been identified. In the present study, we investigated the effects of central administration of glucagon on food intake in chicks. In tracerebroventricular administration of glucagon in chicks significantly suppressed food intake and significantly induced hyperglycemia. In contrast, peripheral administration of the same dose of glucagon did not influence food intake and plasma glucose concentration. These results suggest that glucagon functions in chicks as an appetite-suppressive peptide in the central nervous system. Intracerebroventricular administration of glucagon in chicks also significantly increased CRF mRNA expression and plasma corticosterone concentration, suggesting that CRF acts as a downstream molecule for a glucagon-induced appetite-suppressive pathway in chicks. It is likely that the induction of hyperglycemia by central administration of glucagon is involved in its anorexigenic action, because peripheral administration of glucose in chicks suppressed food intake. These results suggest that CRF-and/or hyperglycemia-mediated pathways are involved in the anorexigenic action of glucagon in chicks.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/9266"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is the author\u0027s version of a work accepted for publication by Elsevier. Changes resulting from the publishing process, including peer review, editing, corrections, structural formatting and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Neuroscience Letters, [VOL 416, ISSUE 2], 2007.", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_text_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Honda, Kazuhisa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21318", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamisoyama, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21319", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, Noboru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21320", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurose, Yohei", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21321", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugahara, Kunio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21322", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hasegawa, Shin", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "21323", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "S_Hasegawa.pdf", "filesize": [{"value": "374.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 374800.0, "url": {"label": "S_Hasegawa.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/7568/files/S_Hasegawa.pdf"}, "version_id": "9d0bb253-976d-4dab-87e1-598ec9390711"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Food intake", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Chicken", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Glucagon", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Hyperglycemia", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Central administration of glucagon suppresses food intake in chicks", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Central administration of glucagon suppresses food intake in chicks", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["667"], "permalink_uri": "http://hdl.handle.net/2237/9266", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-01-10"}, "publish_date": "2008-01-10", "publish_status": "0", "recid": "7568", "relation": {}, "relation_version_is_last": true, "title": ["Central administration of glucagon suppresses food intake in chicks"], "weko_shared_id": -1}