{"created":"2021-03-01T06:16:18.843594+00:00","id":9539,"links":{},"metadata":{"_buckets":{"deposit":"25ae43b3-b64e-481b-b153-399dbf0f3403"},"_deposit":{"created_by":17,"id":"9539","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"9539"},"status":"published"},"_oai":{"id":"oai:nagoya.repo.nii.ac.jp:00009539","sets":["499:508:509:1110"]},"author_link":["27534","27535","27536","27537","27538","27539","27540"],"item_1615768549627":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_9_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"18","bibliographicPageStart":"11","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"Nagoya Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_9_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A mouse jejunum, when incubated in vitro in Ussing chambers, was found to exhibit morphological deterioration of the villi with denudation of the epithelia (J Nutr Sci Vitaminol, 51: 406, 2005). Our study examined the involvement of apoptosis in an intestinal injury model by a DNA ladder assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay. Electrophoresis of mucosal DNA revealed ladders, indicating the occurrence of DNA fragmentation. Cells with TUNEL-positive nuclei were detected among the villus epithelial cells (enterocytes), whereas they are rarely seen among crypt epithelial cells. These features were evident within 1 h after the start of incubation. Apoptotic death of the enterocytes was thus involved in the destruction of villi when incubated in Ussing chambers.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_9_identifier_60":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2237/11332"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18999/nagjms.71.1-2.11","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagoya University School of Medicine","subitem_publisher_language":"en"}]},"item_9_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_9_source_id_61":{"attribute_name":"ISSN（Online）","attribute_value_mlt":[{"subitem_source_identifier":"2186-3326","subitem_source_identifier_type":"EISSN"}]},"item_9_source_id_7":{"attribute_name":"ISSN（print）","attribute_value_mlt":[{"subitem_source_identifier":"0027-7622","subitem_source_identifier_type":"PISSN"}]},"item_9_text_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_text_value":"application/pdf"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"INAGAKI-TACHIBANA, EIKO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27534","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TSUKAHARA, TAKAMITSU","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27535","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KAJI, KAZUHIKO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27536","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"EGUCHI, RYOJI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27537","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KANAZAWA, HIROAKI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27538","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HAYASHI, HISAYOSHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27539","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SUZUKI, YUICHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27540","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-20"}],"displaytype":"detail","filename":"p011-018_Tachibana.pdf","filesize":[{"value":"611.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"p011-018_Tachibana.pdf","objectType":"fulltext","url":"https://nagoya.repo.nii.ac.jp/record/9539/files/p011-018_Tachibana.pdf"},"version_id":"32785a69-6020-40e4-8cb6-730cca8f15d4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Apoptosis","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA ladder","subitem_subject_scheme":"Other"},{"subitem_subject":"TUNEL staining","subitem_subject_scheme":"Other"},{"subitem_subject":"Villus","subitem_subject_scheme":"Other"},{"subitem_subject":"Intestinal barrier","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS","subitem_title_language":"en"}]},"item_type_id":"9","owner":"17","path":["1110"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-16"},"publish_date":"2009-03-16","publish_status":"0","recid":"9539","relation_version_is_last":true,"title":["INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-16T06:34:49.809272+00:00"}