{"_buckets": {"deposit": "924647cc-e268-4e15-840a-11ea13a3f5eb"}, "_deposit": {"id": "10286", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10286"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00010286"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-11", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "490", "bibliographicPageStart": "487", "bibliographic_titles": [{"bibliographic_title": "International Symposium on Micro-NanoMechatronics and Human Science (MHS 2008)"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent a renewable cellular resources for regenerative therapies. Here, we try to differentiate ES cells to paraxial mesodermal progenitors cells (PMPs), which give rise to osteogenic and chondrogenic progenitors and myogenic progenitors without fetal calf serum. Here, we demonstrate the methods for inducing paraxial mesodermal progenitors efficiently by treatment of BMP4 using PDGFR-a and ECD as markers for purifying them. The BMP4 induced PMPs exhibit fine potentials of \ndifferentiation to osto-and chondro-genic cells. Furthermore, early extraction of BMP4 and additional LiCl treatment promote the differentiation of myogenic progenitor cells. Further addition of IGF-1, bFGF and HGF \ninduced the differentiation of PMPs to myocytes in vitro.", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://dx.doi.org/10.1109/MHS.2008.4752501"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/12106"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "IEEE"}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "Copyright \u00a9 2008 IEEE. Reprinted from International Symposium on Micro-NanoMechatronics and Human Science, 2008. MHS 2008, p.487-490.\nThis material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Nagoya University\u2019s products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org."}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sakurai, Hidetoshi"}], "nameIdentifiers": [{"nameIdentifier": "31189", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Inami, Yuta"}], "nameIdentifiers": [{"nameIdentifier": "31190", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishio, Naomi"}], "nameIdentifiers": [{"nameIdentifier": "31191", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshikai, Tohru"}], "nameIdentifiers": [{"nameIdentifier": "31192", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Isobe, Ken-Ichi"}], "nameIdentifiers": [{"nameIdentifier": "31193", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "IEEEd.pdf", "filesize": [{"value": "2.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2000000.0, "url": {"label": "IEEEd.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/10286/files/IEEEd.pdf"}, "version_id": "2f14b24e-f697-45e0-9023-471aec6cefce"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium"}]}, "item_type_id": "10", "owner": "1", "path": ["499/851/1139"], "permalink_uri": "http://hdl.handle.net/2237/12106", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2009-08-27"}, "publish_date": "2009-08-27", "publish_status": "0", "recid": "10286", "relation": {}, "relation_version_is_last": true, "title": ["Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium"], "weko_shared_id": null}