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  1. C100 医学部/医学系研究科
  2. C100e 会議資料
  3. 国際会議

Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium

http://hdl.handle.net/2237/12106
http://hdl.handle.net/2237/12106
d911da51-a1b5-4cc3-9487-833d08be2c8a
名前 / ファイル ライセンス アクション
IEEEd.pdf IEEEd.pdf (2.0 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2009-08-27
タイトル
タイトル Efficient induction of osteogenic and chondrogenic progenitors and myogenic progenitors from mouse ES cells in chemically defined medium
言語 en
著者 Sakurai, Hidetoshi

× Sakurai, Hidetoshi

WEKO 31189

en Sakurai, Hidetoshi

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Inami, Yuta

× Inami, Yuta

WEKO 31190

en Inami, Yuta

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Nishio, Naomi

× Nishio, Naomi

WEKO 31191

en Nishio, Naomi

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Yoshikai, Tohru

× Yoshikai, Tohru

WEKO 31192

en Yoshikai, Tohru

Search repository
Isobe, Ken-Ichi

× Isobe, Ken-Ichi

WEKO 31193

en Isobe, Ken-Ichi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 Copyright © 2008 IEEE. Reprinted from International Symposium on Micro-NanoMechatronics and Human Science, 2008. MHS 2008, p.487-490.
This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Nagoya University’s products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org.
抄録
内容記述 Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent a renewable cellular resources for regenerative therapies. Here, we try to differentiate ES cells to paraxial mesodermal progenitors cells (PMPs), which give rise to osteogenic and chondrogenic progenitors and myogenic progenitors without fetal calf serum. Here, we demonstrate the methods for inducing paraxial mesodermal progenitors efficiently by treatment of BMP4 using PDGFR-a and ECD as markers for purifying them. The BMP4 induced PMPs exhibit fine potentials of differentiation to osto-and chondro-genic cells. Furthermore, early extraction of BMP4 and additional LiCl treatment promote the differentiation of myogenic progenitor cells. Further addition of IGF-1, bFGF and HGF induced the differentiation of PMPs to myocytes in vitro.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 IEEE
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1109/MHS.2008.4752501
書誌情報 en : International Symposium on Micro-NanoMechatronics and Human Science (MHS 2008)

p. 487-490, 発行日 2008-11
著者版フラグ
値 author
URI
識別子 http://hdl.handle.net/2237/12106
識別子タイプ HDL
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