{"_buckets": {"deposit": "a8b7741e-723e-4b7b-906e-353be53e806c"}, "_deposit": {"id": "11048", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "11048"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00011048"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1-2", "bibliographicPageEnd": "70", "bibliographicPageStart": "59", "bibliographicVolumeNumber": "72", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Osteogenic cells have been found within periosteal tissue. Periosteal cells will also form a membranous structure under the appropriate culture conditions. We have characterized the osteogenic potential of this membranous cultured periosteum (CP) and have demonstrated that CP can successfully regenerate alveolar bone defects in a canine periodontitis model. The aim of this study is to demonstrate periodontal tissue\nregeneration by using CP for patients with severe periodontitis. CP was applied in treatments for severe alveolar bone defects for a total of seven teeth among four periodontitis patients. Bone formation was evaluated by dental radiography 4 months after grafting, with a follow-up period of 12 to 15 months. CP was successfully generated and formed a membrane (approximately 4 cm in diameter) about 4 weeks after attachment to the dish. Vertical bone gain (3 to 8 mm) was observed in all grafted areas at 4 months post-surgery. The probing depth was also reduced to its normal depth and remained so beyond one year.\nResults from the present cases suggest that periodontitis patients with bone defects can benefit from CP treatment. Post-operative evaluation indicates periodontal tissue regeneration after CP treatment, suggesting\na broad application for patients with periodontal disease.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/12910"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.72.1-2.59", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University School of Medicine"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Mizuno, Hirokazu"}], "nameIdentifiers": [{"nameIdentifier": "33497", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kagami, Hideaki"}], "nameIdentifiers": [{"nameIdentifier": "33498", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mase, Junji"}], "nameIdentifiers": [{"nameIdentifier": "33499", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizuno, Daiki"}], "nameIdentifiers": [{"nameIdentifier": "33500", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueda, Minoru"}], "nameIdentifiers": [{"nameIdentifier": "33501", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "p059-070_Mizuno.pdf", "filesize": [{"value": "818.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 818000.0, "url": {"label": "p059-070_Mizuno.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/11048/files/p059-070_Mizuno.pdf"}, "version_id": "3fc643ed-6763-430c-abdf-c00552e23b8e"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Cultured periosteum", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Guided tissue regeneration", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Platelet-rich plasma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Periodontal tissue", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Regeneration", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Efficacy of Membranous Cultured Periosteum for the Treatment of Patients with Severe Periodontitis: a Proof-of-Concept Study", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Efficacy of Membranous Cultured Periosteum for the Treatment of Patients with Severe Periodontitis: a Proof-of-Concept Study"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/1196"], "permalink_uri": "https://doi.org/10.18999/nagjms.72.1-2.59", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2010-03-11"}, "publish_date": "2010-03-11", "publish_status": "0", "recid": "11048", "relation": {}, "relation_version_is_last": true, "title": ["Efficacy of Membranous Cultured Periosteum for the Treatment of Patients with Severe Periodontitis: a Proof-of-Concept Study"], "weko_shared_id": null}